Catharanthine Sulfate | CAS:70674-90-7

Catharanthine Sulfate

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Description:

Catharanthine Sulfate is a natural product from Catharanthus roseus (L.) G.Don.

In vitro:

Chromatographia, 2012 , 75 (1-2) :25-32.

A Convenient Approach to Simultaneous Analysis of a Pharmaceutical Drug and Its Counter-Ion by CE Using Dual-Opposite End Injection and Contactless Conductivity Detection[Reference: WebLink]

Capillary electrophoresis (CE) coupled to a capacitively coupled contactless conductivity detector (C4D) was used for the determination in a single analysis of a pharmaceutical drug and its counter-ion.
METHODS AND RESULTS:
Dual-opposite end injection (DOI) was used to introduce hydrodynamically the analytes at each end of the capillary. No modification of the commercial apparatus is required. After applying the voltage, the cations and anions migrate from each end of the capillary in opposite directions toward the detector placed near the cathode outlet. The electrophoretic conditions were initially developed with three test drugs (chlorpheniramine maleate, metoprolol tartrate, clomiphene citrate) and then applied to two Vinca alkaloids (Catharanthine Sulfate, vinorelbine ditartrate). The 10 mM histidine–50 mM acetic acid buffer (pH 4.1)–methanol 90:10 (v/v) electrolyte was suitable for the analysis of these high or medium mobile anions by CE–C4D due to its low conductivity background and high buffer capacity. Finally, the CE procedure developed was successfully validated for Catharanthine Sulfate.
CONCLUSIONS:
The method developed herein is fast (<10 min) and accurate (repeatability on migration time < 0.6% and peak areas < 1.3%, n = 6).

Catharanthine Sulfate Description

Source:	The herbs of Catharanthus roseus (L.) G.Don
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Catharanthine Sulfate
Price:
CAS No.:	70674-90-7
Catalog No.:	CFN93298
Molecular Formula:	C₂₁H₂₆N₂O₆S
Molecular Weight:	434.51 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The herbs of Catharanthus roseus (L.) G.Don
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Alkaloids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.3014 mL	11.5072 mL	23.0144 mL	46.0289 mL	57.5361 mL
5 mM	0.4603 mL	2.3014 mL	4.6029 mL	9.2058 mL	11.5072 mL
10 mM	0.2301 mL	1.1507 mL	2.3014 mL	4.6029 mL	5.7536 mL
50 mM	0.046 mL	0.2301 mL	0.4603 mL	0.9206 mL	1.1507 mL
100 mM	0.023 mL	0.1151 mL	0.2301 mL	0.4603 mL	0.5754 mL

CFN96649	Tabernanthine	83-94-3	310.44	C₂₀H₂₆N₂O
CFN92252	Voacangine	510-22-5	368.5	C₂₂H₂₈N₂O₃
CFN96068	Conopharyngine	76-98-2	398.5	C₂₃H₃₀N₂O₄
CFN96069	19(S)-Hydroxyconopharyngine	16790-93-5	414.5	C₂₃H₃₀N₂O₅
CFN96176	Crassanine	16790-92-4	414.5	C₂₃H₃₀N₂O₅
CFN99765	Catharanthine	2468-21-5	336.43	C₂₁H₂₄N₂O₂
CFN90318	Catharanthine Tartrate	2648-21-5	486.40	C₂₁H₂₄N₂O₂.C₄H₆O₆
CFN93298	Catharanthine Sulfate	70674-90-7	434.51	C₂₁H₂₆N₂O₆S
CFN98432	19,20-(E)-Vallesamine	3368-87-4	340.4	C₂₀H₂₄N₂O₃
CFN99377	Vallesamine N-oxide	126594-73-8	356.4	C₂₀H₂₄N₂O₄