Citrostadienol | CAS:474-40-8 | Manufacturer ChemFaces

Citrostadienol

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Description:

Citrostadienol shows cytotoxic activity against B16F10 melanoma cells.

In vitro:

J Ethnopharmacol. 2013 Oct 28;150(1):263-9.

Antitumoural effect of Synadenium grantii Hook f. (Euphorbiaceae) latex.[Pubmed: 24008110]

METHODS AND RESULTS:
The Synadenium grantii latex exhibited decreased cell viability of the melanoma line in a concentration and time-dependent manner, and also cell cycle arrest in the S-G2/M phase. The latex caused a 40% reduction in the volume of tumours of the mice with melanomas. Histological examination of the organs of these animals showed no differences between groups. The phytochemical investigation resulted in the isolation and identification of triterpene euphol and the steroid Citrostadienol, which were tested against the strain of melanoma. Euphol showed no antitumoural activity, while the steroid Citrostadienol showed reduced cytotoxic activity.
CONCLUSIONS:
The Synadenium grantii latex presented in vitro and in vivo cytotoxic effects with antitumoural activity against B16F10 melanoma cells.

Citrostadienol Description

Source:	The herbs of Prunus armeniaca L.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Nat Prod Res. 2017 Jan;31(1):84-88.

Sterols and squalene in apricot (Prunus armeniaca L.) kernel oils: the variety as a key factor.[Pubmed: 26745662]

METHODS AND RESULTS:
The profile of sterols and squalene content in oils recovered from the kernels of 15 apricot (Prunus armeniaca L.) varieties were investigated. Nine sterols (campesterol, β-sitosterol, Δ5-avenasterol, 24-methylene-cycloartanol, cholesterol, gramisterol, Δ7-stigmasterol, Δ7-avenasterol and Citrostadienol) were identified in apricot kernel oils.
CONCLUSIONS:
The β-sitosterol was the predominant sterol in each cultivar and consisted of 76-86% of the total detected sterols. The content of total sterols and squalene were significantly affected by the variety and ranged between 215.7-973.6 and 12.6-43.9 mg/100 g of oil, respectively.

Product Name	Citrostadienol
Price:
CAS No.:	474-40-8
Catalog No.:	CFN89063
Molecular Formula:	C₃₀H₅₀O
Molecular Weight:	426.72 g/mol
Purity:	>=98%
Type of Compound:	Steroids
Physical Desc.:	Powder
Source:	The herbs of Prunus armeniaca L.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Cytotoxic Compound Library Steroids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.3435 mL	11.7173 mL	23.4346 mL	46.8691 mL	58.5864 mL
5 mM	0.4687 mL	2.3435 mL	4.6869 mL	9.3738 mL	11.7173 mL
10 mM	0.2343 mL	1.1717 mL	2.3435 mL	4.6869 mL	5.8586 mL
50 mM	0.0469 mL	0.2343 mL	0.4687 mL	0.9374 mL	1.1717 mL
100 mM	0.0234 mL	0.1172 mL	0.2343 mL	0.4687 mL	0.5859 mL

CFN92239	Delta 5-avenasterol	18472-36-1	412.7	C₂₉H₄₈O
CFN92240	Delta 7-avenasterol	23290-26-8	412.7	C₂₉H₄₈O
CFN90787	Clerosterol	2364-23-0	412.7	C₂₉H₄₈O
CFN98304	22-Dehydroclerosterol	26315-07-1	410.7	C₂₉H₄₆O
CFN98350	22-Dehydroclerosteryl acetate	28594-00-5	452.7	C₃₁H₄₈O₂
CFN99498	3beta-Hydroxyporiferast-5-en-7-one	145163-97-9	428.7	C₂₉H₄₈O₂
CFN89063	Citrostadienol	474-40-8	426.72	C₃₀H₅₀O