Dihydroconiferyl alcohol | CAS:2305-13-7

Dihydroconiferyl alcohol

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Description:

Dihydroconiferyl alcohol exhibits cytoprotective activity in cultured MCF-7 cells stressed by H2O2.

In vitro:

J Agric Food Chem. 2008 Sep 10;56(17):7759-64.

Lignans and other constituents of the fruits of Euterpe oleracea (Acai) with antioxidant and cytoprotective activities.[Pubmed: 18656934 ]

METHODS AND RESULTS:
Using a hydroxyl radical scavenging assay, bioactivity-guided fractionation of a methanol-soluble extract of the fruits of Euterpe oleracea (acai) led to the isolation of 22 compounds of previously known structure. Altogether, 14 of these isolates were found to be active in an in vitro hydroxyl radical scavenging assay and seven of these isolates in a 1,1-diphenyl-2-picrylhydrazyl radical scavenging assay. Dihydroconiferyl alcohol, (+)-lariciresinol, (+)-pinoresinol, (+)-syringaresinol, and protocatechuic acid methyl ester exhibited cytoprotective activity in cultured MCF-7 cells stressed by H2O2.
CONCLUSIONS:
Lignans have not been previously reported as constituents of this species and were found to be representative of the aryltetrahydronaphthalene, dihydrobenzofuran, furofuran, 8-O-4'-neolignan, and tetrahydrofuran structural types.

Dihydroconiferyl alcohol Description

Source:	The roots of Taraxacum coreanum.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Molecules. 2017 Aug 14;22(8).

Inositol Derivatives and Phenolic Compounds from the Roots of Taraxacum coreanum.[Pubmed: 28805750 ]

METHODS AND RESULTS:
In this study, the characterization of chemical constituents and biological activity of the roots of Taraxacum coreanum (Asteraceae) was attempted. Phytochemical investigation of the roots of T. coreanum led to the isolation of two new inositol derivatives, taraxinositols A (1) and B (2), and a new phenolic compound, taraxinol (16), together with twenty known compounds including four inositol derivatives, neo-inositol-1,4-bis (4-hydroxybenzeneacetate) (3), chiro-inositol-1,5-bis(4- hydroxybenzeneacetate) (4), chiro-inositol-2,3-bis (4-hydroxybenzeneacetate) (5) and chiro-inositol- 1,2,3-tris (4-hydroxybenzeneacetate) (6), nine phenolic compounds: p-hydroxybenzaldehyde (7), vanillin (8), syringaldehyde (9), vanillic acid (10), 4-methoxyphenylacetic acid (11), 4-hydroxy- phenylacetic acid methyl ester (12), optivanin (13), isoferulic acid (14) and Dihydroconiferyl alcohol (15), four coumarins: nodakenetin (17), decursinol (18), prangol (19) and isobyakangelicin (20), and three lignans: syringaresinol-4'-O-β-d-glucoside (21), syringaresinol (22), and pinoresinol (23). The structures of isolated compounds were determined on the basis of spectroscopic analysis.
CONCLUSIONS:
Among the isolated compounds, vanillic acid, isoferulic acid and syringaresinol showed radical scavenging activity with IC50 values ranging from 30.4 to 75.2 μM.

Product Name	Dihydroconiferyl alcohol
Price:
CAS No.:	2305-13-7
Catalog No.:	CFN96742
Molecular Formula:	C₁₀H₁₄O₃
Molecular Weight:	182.21 g/mol
Purity:	>=98%
Type of Compound:	Phenylpropanoids
Physical Desc.:	Powder
Source:	The roots of Taraxacum coreanum.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Cytoprotective Compound Library Phenylpropanoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	5.4882 mL	27.4409 mL	54.8817 mL	109.7635 mL	137.2043 mL
5 mM	1.0976 mL	5.4882 mL	10.9763 mL	21.9527 mL	27.4409 mL
10 mM	0.5488 mL	2.7441 mL	5.4882 mL	10.9763 mL	13.7204 mL
50 mM	0.1098 mL	0.5488 mL	1.0976 mL	2.1953 mL	2.7441 mL
100 mM	0.0549 mL	0.2744 mL	0.5488 mL	1.0976 mL	1.372 mL

CFN96771	Acetylisoeugenol	93-29-8	206.24	C₁₂H₁₄O₃
CFN98088	beta-Hydroxypropiovanillone	2196-18-1	196.2	C₁₀H₁₂O₄
CFN94482	Dihydrosinapylalcohol	20736-25-8	212.24	C₁₁H₁₆O₄
CFN97826	3,4'-Dihydroxy-3',5'-dimethoxypropiophenone	136196-47-9	226.23	C₁₁H₁₄O₅
CFN98379	3,4,5-Trimethoxycinnamyl alcohol	30273-62-2	224.3	C₁₂H₁₆O₄
CFN98675	3-Phenyl-2-propen-1-ol	4407-36-7	134.2	C₉H₁₀O
CFN98057	Cinnamyl acetate	21040-45-9	176.2	C₁₁H₁₂O₂
CFN99037	3-(4-Hydroxyphenyl)-1-propanol	10210-17-0	152.2	C₉H₁₂O₂
CFN96011	p-Coumaryl alcohol	3690-05-9	150.2	C₉H₁₀O₂
CFN89230	4-Methoxycinnamyl alcohol	53484-50-7	164.20	C₁₀H₁₂O₂