Glochicoccin D | CAS:927812-23-5 | Manufacturer ChemFaces

Glochicoccin D

ChemFaces products have been cited in many studies from excellent and top scientific journals

Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC

How to Order

Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com

Delivery time

Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal

Citing Use of our Products

More Impact Factor than five Cite...

* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.

According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

Featured Products

More...

Caftaric acid

Catalog No: CFN00384
CAS No: 67879-58-7
Price: $138/20mg

Rutaecarpine

Catalog No: CFN97337
CAS No: 84-26-4
Price: $40/20mg

Octahydrocurcumin

Catalog No: CFN90584
CAS No: 36062-07-4
Price: $388/20mg

beta-Eudesmol

Catalog No: CFN99537
CAS No: 473-15-4
Price: $288/20mg

Vaccarin

Catalog No: CFN90131
CAS No: 53452-16-7
Price: $30/20mg

Zearalenone

Catalog No: CFN91172
CAS No: 17924-92-4
Price: $50/20mg

Ginsenoside F1

Catalog No: CFN99754
CAS No: 53963-43-2
Price: $90/20mg

Punicalagin

Catalog No: CFN99938
CAS No: 65995-63-3
Price: $108/20mg

Neoandrographolide

Catalog No: CFN97766
CAS No: 27215-14-1
Price: $60/20mg

Asiaticoside B

Catalog No: CFN95124
CAS No: 125265-68-1
Price: $158/20mg

Description:

Standard reference

In vitro:

Org Biomol Chem. 2014 Nov 21;12(43):8764-74.

Anti-hepatitis B virus activities and absolute configurations of sesquiterpenoid glycosides from Phyllanthus emblica.[Pubmed: 25268491]

METHODS AND RESULTS:
During the process exploring anti-viral compounds from Phyllanthus species, eight new highly oxygenated bisabolane sesquiterpenoid glycoside phyllaemblicins G1–G8 (1–8) were isolated from Phyllanthus emblica, along with three known compounds, phyllaemblicin F (9), phyllaemblic acid (10) and Glochicoccin D (11). Phyllaemblicin G2 (2), bearing a tricyclo [3.1.1.1] oxygen bridge ring system, is an unusual sesquiterpenoid glycoside, while phyllaemblicins G6–G8 (6–8) are dimeric sesquiterpenoid glycosides with two norbisabolane units connecting through a disaccharide. All the structures were elucidated by the extensive analysis of HRMS and NMR data. The relative configuration of phyllaemblicin G2 was constructed based on heteronuclear coupling constants measurement, and the absolute configurations for all new compounds were established by calculated electronic circular dichroism (ECD) using time dependent density functional theory.
CONCLUSIONS:
The sesquiterpenoid glycoside dimers 6–9 displayed potential anti-hepatitis B virus (HBV) activities, especially for the new compound 6 with IC50 of 8.53 ± 0.97 and 5.68 ± 1.75 μM towards the HBV surface antigen (HBsAg) and HBV excreted antigen (HBeAg) secretion, respectively.

Glochicoccin D Description

Source:	The fruits of Phyllanthus emblica L.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

J Org Chem. 2010 Nov 5;75(21):7461-4.

Stereoselective α,α'-annelation reactions of 1,3-dioxan-5-ones.[Pubmed: 20936869 ]

METHODS AND RESULTS:
Pyrrolidine enamines derived from three 1,3-dioxan-5-ones undergo α,α'-annelation reactions with methyl α-(bromomethyl)acrylate to produce bridged 2,4-dioxabicyclo[3.3.1]nonane ring systems with complete stereocontrol. Stereochemical outcomes have been rationalized based on steric and stereoelectronic interactions in intermediate boat-like conformations of the 1,3-dioxane ring and subsequent kinetic protonation to set an axial ester group on the cyclohexanone ring.
CONCLUSIONS:
Base-mediated ester epimerization provides the stereochemical array found in the highly oxygenated cyclohexane ring of phyllaemblic acid and glochicoccin B and Glochicoccin D.

Product Name	Glochicoccin D
Price:
CAS No.:	927812-23-5
Catalog No.:	CFN97495
Molecular Formula:	C₂₁H₂₄O₁₀
Molecular Weight:	436.4 g/mol
Purity:	>=98%
Type of Compound:	Miscellaneous
Physical Desc.:	Powder
Source:	The fruits of Phyllanthus emblica L.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Miscellaneous Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.2915 mL	11.4574 mL	22.9148 mL	45.8295 mL	57.2869 mL
5 mM	0.4583 mL	2.2915 mL	4.583 mL	9.1659 mL	11.4574 mL
10 mM	0.2291 mL	1.1457 mL	2.2915 mL	4.583 mL	5.7287 mL
50 mM	0.0458 mL	0.2291 mL	0.4583 mL	0.9166 mL	1.1457 mL
100 mM	0.0229 mL	0.1146 mL	0.2291 mL	0.4583 mL	0.5729 mL

CFN98579	Bakkenolide A	19906-72-0	234.34	C₁₅H₂₂O₂
CFN96942	Bakkenolide III	24909-95-3	266.33	C₁₅H₂₂O₄
CFN96812	1-Oxobakkenolide S	18456-02-5	264.32	C₁₅H₂₀O₄
CFN96902	Bakkenolide B	18455-98-6	390.47	C₂₂H₃₀O₆
CFN89054	Bakkenolide IIIa	915289-60-0	448.57	C₂₄H₃₂O₆S
CFN90795	Bakkenolide D	18456-03-6	408.5	C₂₁H₂₈O₆S
CFN96815	Bakkenolide Db	226711-23-5	424.50	C₂₁H₂₈O₇S
CFN97495	Glochicoccin D	927812-23-5	436.4	C₂₁H₂₄O₁₀
CFN99518	Muscone	541-91-3	238.42	C₁₆H₃₀O
CFN92687	Officinaruminane B	1246282-67-6	400.6	C₂₉H₃₆O