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Hedyotisol A
Hedyotisol A
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Hedyotisol A
Price:
CAS No.: 95732-59-5
Catalog No.: CFN97537
Molecular Formula: C42H50O16
Molecular Weight: 810.9 g/mol
Purity: >=98%
Type of Compound: Lignans
Physical Desc.: Powder
Source: The herbs of Cocculus orbiculatus.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Hedyotisol A is a natural product from Cocculus orbiculatus.
Hedyotisol A Description
Source: The herbs of Cocculus orbiculatus.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.2332 mL 6.166 mL 12.332 mL 24.664 mL 30.8299 mL
5 mM 0.2466 mL 1.2332 mL 2.4664 mL 4.9328 mL 6.166 mL
10 mM 0.1233 mL 0.6166 mL 1.2332 mL 2.4664 mL 3.083 mL
50 mM 0.0247 mL 0.1233 mL 0.2466 mL 0.4933 mL 0.6166 mL
100 mM 0.0123 mL 0.0617 mL 0.1233 mL 0.2466 mL 0.3083 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chemical & Pharmaceutical Bulletin, 2008, 32 (12):5066-9.
Isolation and structures of hedyotisol-A, -B, and -C novel dilignans from Hedyotis lawsoniae.[Reference: WebLink]

METHODS AND RESULTS:
Three new dilignans, Hedyotisol A (1a), hedyotisol B (2a), and hedyotisol C (3a), were isolated from the leaves of Hedyotis lawsoniae and their structures were examined.
CONCLUSIONS:
These compounds are constructed from a syringaresinol unit and two phenylpropane units, and they are stereoisomeric with each other.
CFN97877Hedyotisol B95839-45-5810.9C42H50O16
CFN99504(-)-Syringaresinol 4-(2''-apiosylglucoside)136997-64-3712.69C33H44O17
CFN92288(+)-Epipinoresinol24404-50-0358.4C20H22O6
CFN89280Kobusin36150-23-9370.40C21H22O6
CFN90144(-)-Asarinin133-04-0354.35C20H18O6
CFN92420(-)-Epipinoresinol10061-38-8358.4C20H22O6
CFN90511Phillygenin487-39-8372.41C21H24O6
CFN99998Phillyrin487-41-2534.56C27H34O11
CFN91840(+)-Mediresinol Di-O-beta-D-glucopyranoside88142-63-6712.7C33H44O17
CFN98174Fargesin31008-19-2370.39C21H22O6
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