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Ilexoside D
Ilexoside D
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Ilexoside D
Price: $268 / 10mg
CAS No.: 109008-27-7
Catalog No.: CFN90993
Molecular Formula: C41H66O13
Molecular Weight: 766.97 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The roots of Ilex pubescens Hook. et Arn.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $230.5 / In-stock
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Ilexoside D has ant-allergic, and anti-coagulant activities, it shows anti-tissue factor activity as well as the antithrombotic activity.
In vitro:
Tetrahedron Letters, 1991, 32(29):3535-3538.
Ilexosides A, B, C and D, anti-allergic 18,19-seco-ursane glycosides from fruit of Ilex crenata.[Reference: WebLink]

METHODS AND RESULTS:
Four novel 18,19-seco-ursane glycosides named ilexoside A, ilexoside B, ilexoside C and Ilexoside D have been isolated from Ilex crenata Thunb.. Their structures were established as novel glycosides of 3β-hydroxy-19-oxo-18,19-seco-11,13(18)-ursadiene-28-oic-acid on the basis of chemical and spectroscopic analysis.
CONCLUSIONS:
They exhibited ant-allergic activities.The ant-alergic effect of Ilexoside A(1) ,ilexoside B(2) ,ilexoside C(3) and Ilexoside D(4) are 10 times as potent as glycyrrhizin.
In vivo:
Archives of Pharmacal Research, 1993, 16(3):209-212.
Anticoagulant activity of ilexoside D, a triterpenoid saponin fromIlex pubescens.[Reference: WebLink]
The anti-coagulant activity of Ilexoside D isolated from the roots ofIlex pubescens Hook. et Arn. was investigated inin vivo andin vitro models of blood coagulation in rats.
METHODS AND RESULTS:
On oral administration, Ilexoside D prolonged the bleeding time and the whole blood recalcified clotting time, but not the plasma recalcified clotting time.In vitro, Ilexoside D did not affect the recalcified clotting times of whole blood, platelet-rich plasma (PRP), and platelet-poor plasma (PPP) while in the presence of tissue factor the compound prolonged the reduced prothrombin times of whole blood, PRP and PPP in the dose-dependent manner.
CONCLUSIONS:
These results indicate that Ilexoside D has the anti-tissue factor activity as well as the antithrombotic activity.
Ilexoside D Description
Source: The roots of Ilex pubescens Hook. et Arn.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.3038 mL 6.5192 mL 13.0383 mL 26.0766 mL 32.5958 mL
5 mM 0.2608 mL 1.3038 mL 2.6077 mL 5.2153 mL 6.5192 mL
10 mM 0.1304 mL 0.6519 mL 1.3038 mL 2.6077 mL 3.2596 mL
50 mM 0.0261 mL 0.1304 mL 0.2608 mL 0.5215 mL 0.6519 mL
100 mM 0.013 mL 0.0652 mL 0.1304 mL 0.2608 mL 0.326 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
CFN98465Ziyuglycoside II35286-59-0604.8 C35H56O8
CFN90993Ilexoside D109008-27-7766.97C41H66O13
CFN92273Ilexside I83725-19-3472.7C41H66O13
CFN90994Ilexoside K109008-26-6929.10C47H76O18
CFN97328Pomolic acid 28-O-beta-D-glucopyranosyl ester83725-24-0634.9 C36H58O9
CFN89311Kaji-ichigoside F195298-47-8650.85C36H58O10
CFN89097Rosamultin88515-58-6650.85C36H58O10
CFN91060Niga-ichigoside F195262-48-9666.9C36H58O11
CFN91067Suavissimoside F195645-51-5680.8C36H56O12
CFN98464Ziyuglycoside I35286-58-9767.0 C41H66O13
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