Ilexoside D | CAS:109008-27-7 | Manufacturer ChemFaces

Ilexoside D

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Size /Price /Stock	10 mM * 1 mL in DMSO / $230.5 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Description:

Ilexoside D has ant-allergic, and anti-coagulant activities, it shows anti-tissue factor activity as well as the antithrombotic activity.

In vitro:

Tetrahedron Letters, 1991, 32(29):3535-3538.

Ilexosides A, B, C and D, anti-allergic 18,19-seco-ursane glycosides from fruit of Ilex crenata.[Reference: WebLink]

METHODS AND RESULTS:
Four novel 18,19-seco-ursane glycosides named ilexoside A, ilexoside B, ilexoside C and Ilexoside D have been isolated from Ilex crenata Thunb.. Their structures were established as novel glycosides of 3β-hydroxy-19-oxo-18,19-seco-11,13(18)-ursadiene-28-oic-acid on the basis of chemical and spectroscopic analysis.
CONCLUSIONS:
They exhibited ant-allergic activities.The ant-alergic effect of Ilexoside A(1) ,ilexoside B(2) ,ilexoside C(3) and Ilexoside D(4) are 10 times as potent as glycyrrhizin.

In vivo:

Archives of Pharmacal Research, 1993, 16(3):209-212.

Anticoagulant activity of ilexoside D, a triterpenoid saponin fromIlex pubescens.[Reference: WebLink]

The anti-coagulant activity of Ilexoside D isolated from the roots ofIlex pubescens Hook. et Arn. was investigated inin vivo andin vitro models of blood coagulation in rats.
METHODS AND RESULTS:
On oral administration, Ilexoside D prolonged the bleeding time and the whole blood recalcified clotting time, but not the plasma recalcified clotting time.In vitro, Ilexoside D did not affect the recalcified clotting times of whole blood, platelet-rich plasma (PRP), and platelet-poor plasma (PPP) while in the presence of tissue factor the compound prolonged the reduced prothrombin times of whole blood, PRP and PPP in the dose-dependent manner.
CONCLUSIONS:
These results indicate that Ilexoside D has the anti-tissue factor activity as well as the antithrombotic activity.

Ilexoside D Description

Source:	The roots of Ilex pubescens Hook. et Arn.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Ilexoside D
Price:	$268 / 10mg
CAS No.:	109008-27-7
Catalog No.:	CFN90993
Molecular Formula:	C₄₁H₆₆O₁₃
Molecular Weight:	766.97 g/mol
Purity:	>=98%
Type of Compound:	Triterpenoids
Physical Desc.:	Powder
Source:	The roots of Ilex pubescens Hook. et Arn.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Anti-allergy Compound Library Antithrombotic Compound Library Anticoagulants Compound Library Triterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.3038 mL	6.5192 mL	13.0383 mL	26.0766 mL	32.5958 mL
5 mM	0.2608 mL	1.3038 mL	2.6077 mL	5.2153 mL	6.5192 mL
10 mM	0.1304 mL	0.6519 mL	1.3038 mL	2.6077 mL	3.2596 mL
50 mM	0.0261 mL	0.1304 mL	0.2608 mL	0.5215 mL	0.6519 mL
100 mM	0.013 mL	0.0652 mL	0.1304 mL	0.2608 mL	0.326 mL

CFN98465	Ziyuglycoside II	35286-59-0	604.8	C₃₅H₅₆O₈
CFN90993	Ilexoside D	109008-27-7	766.97	C₄₁H₆₆O₁₃
CFN92273	Ilexside I	83725-19-3	472.7	C₄₁H₆₆O₁₃
CFN90994	Ilexoside K	109008-26-6	929.10	C₄₇H₇₆O₁₈
CFN97328	Pomolic acid 28-O-beta-D-glucopyranosyl ester	83725-24-0	634.9	C₃₆H₅₈O₉
CFN89311	Kaji-ichigoside F1	95298-47-8	650.85	C₃₆H₅₈O₁₀
CFN89097	Rosamultin	88515-58-6	650.85	C₃₆H₅₈O₁₀
CFN91060	Niga-ichigoside F1	95262-48-9	666.9	C₃₆H₅₈O₁₁
CFN91067	Suavissimoside F1	95645-51-5	680.8	C₃₆H₅₆O₁₂
CFN98464	Ziyuglycoside I	35286-58-9	767.0	C₄₁H₆₆O₁₃