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Ilexoside XLVIII
Ilexoside XLVIII
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Ilexoside XLVIII
Price: $318 / 5mg
CAS No.: 129095-76-7
Catalog No.: CFN91698
Molecular Formula: C42H66O15
Molecular Weight: 811.0 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The roots of Ilex pubescens.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $508.8 / In-stock
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Ilexoside XLVIII is an acyl CoA cholesteryl acyl transferase (ACAT) inhibitor. Ilexoside XLVIII is a triterpene saponin isolated from an aqueous extract of the leaves of Ilex kudincha.
Ilexoside XLVIII Description
Source: The roots of Ilex pubescens.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.233 mL 6.1652 mL 12.3305 mL 24.6609 mL 30.8261 mL
5 mM 0.2466 mL 1.233 mL 2.4661 mL 4.9322 mL 6.1652 mL
10 mM 0.1233 mL 0.6165 mL 1.233 mL 2.4661 mL 3.0826 mL
50 mM 0.0247 mL 0.1233 mL 0.2466 mL 0.4932 mL 0.6165 mL
100 mM 0.0123 mL 0.0617 mL 0.1233 mL 0.2466 mL 0.3083 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
J Nat Prod . 1999 Aug;62(8):1128-1133.
Triterpenoid saponins from Ilex kudincha[Pubmed: 10479318]
Ten new triterpene saponins, ilekudinosides A-J (2, 6-8, 10, 13-17), together with seven known triterpene saponins, Ilexoside XLVIII (1); cynarasaponin C (5); latifolosides A (9), C (3), G (12), and H (4); and kudinoside G (11), were isolated from an aqueous extract of the leaves of Ilex kudincha. They possessed oleanane- and ursane-type triterpenoids as the aglycons. The structures were elucidated by 1D and 2D NMR experiments, including ROE difference, HOHAHA difference, 1H-1H COSY, and 1H-13C COSY (HMQC, HMBC) methods and sugar analysis. Compounds 1 and 5 exhibited acyl CoA cholesteryl acyl transferase (ACAT) inhibitory activity.
L-Nicotine

Catalog No: CFN99512
CAS No: 54-11-5
Price: $40/20mg
Salicylic acid

Catalog No: CFN93274
CAS No: 69-72-7
Price: $30/20mg
Petunidin chloride

Catalog No: CFN92036
CAS No: 1429-30-7
Price: $488/5mg
Grossamide

Catalog No: CFN97672
CAS No: 80510-06-1
Price: $318/5mg
Physalin B

Catalog No: CFN92941
CAS No: 23133-56-4
Price: $ / mg
Rosmarinyl glucoside

Catalog No: CFN95297
CAS No: 910028-78-3
Price: $413/5mg
Anethole

Catalog No: CFN98550
CAS No: 104-46-1
Price: $30/20mg
Soybean phospholipid

Catalog No: CFN93800
CAS No: 8002-43-5
Price: $30/20mg
Dehydrotrametenolic acid

Catalog No: CFN90577
CAS No: 29220-16-4
Price: $188/20mg
Ononin

Catalog No: CFN99136
CAS No: 486-62-4
Price: $50/20mg
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