Science | Nature | Cell | View More
Natural Products
Ligularine
Ligularine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Ligularine
Price:
CAS No.: 34429-54-4
Catalog No.: CFN00378
Molecular Formula: C19H27NO7
Molecular Weight: 381.4 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Ligularia hodgsonii.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
More Impact Factor than five Cite...
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Our products had been exported to the following research institutions and universities, And still growing.
  • University of Vienna (Austria)
  • Universidad de Buenos Aires (Argentina)
  • Anna University (India)
  • Universit?t Basel (Switzerland)
  • University of Oslo (Norway)
  • Semmelweis Unicersity (Hungary)
  • University of Brasilia (Brazil)
  • University of Medicine and Phar... (Romania)
  • University of Dicle (Turkey)
  • University of South Australia (Australia)
  • Helmholtz Zentrum München (Germany)
  • More...
Package
Featured Products
More...
Cinnamic acid

Catalog No: CFN99453
CAS No: 140-10-3
Price: $30/20mg
Kukoamine B

Catalog No: CFN93216
CAS No: 164991-67-7
Price: $268/10mg
Isochlorogenic acid C

Catalog No: CFN99120
CAS No: 32451-88-0
Price: $70/20mg
Aloenin A

Catalog No: CFN93235
CAS No: 38412-46-3
Price: $ / mg
Fraxetin

Catalog No: CFN99113
CAS No: 574-84-5
Price: $30/20mg
Timosaponin A3

Catalog No: CFN98151
CAS No: 41059-79-4
Price: $50/20mg
Solasodine

Catalog No: CFN90200
CAS No: 126-17-0
Price: $168/20mg
Oleuropein

Catalog No: CFN98416
CAS No: 32619-42-4
Price: $30/20mg
Gracillin

Catalog No: CFN98537
CAS No: 19083-00-2
Price: $80/20mg
(-)-Gallocatechin

Catalog No: CFN99137
CAS No: 3371-27-5
Price: $128/20mg
Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Ligularine and clivorine are two hepatotoxic otonecine-type pyrrolizidine alkaloids.
Ligularine Description
Source: The herbs of Ligularia hodgsonii.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
New Products More...
Ganoderic acid Df

Catalog No: CFN95514
CAS No: 1352033-73-8
Price: $318/5mg
Isophysalin G

Catalog No: CFN95328
CAS No: 152221-21-1
Price: $368/5mg
Clemastanin B

Catalog No: CFN95064
CAS No: 112747-98-5
Price: $368/20mg
Ganoderic acid L

Catalog No: CFN95022
CAS No: 102607-24-9
Price: $413/5mg
8-Epiloganin

Catalog No: CFN95478
CAS No: 79172-04-6
Price: $318/20mg
Catechin 7-O-beta-D-glucopyranosid...

Catalog No: CFN95524
CAS No: 65597-47-9
Price: $338/20mg
2'-Rhamnoechinacoside

Catalog No: CFN95035
CAS No: 1422390-59-7
Price: $368/10mg
Fragransin B1

Catalog No: CFN95443
CAS No: 112516-03-7
Price: $318/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.6219 mL 13.1096 mL 26.2192 mL 52.4384 mL 65.548 mL
5 mM 0.5244 mL 2.6219 mL 5.2438 mL 10.4877 mL 13.1096 mL
10 mM 0.2622 mL 1.311 mL 2.6219 mL 5.2438 mL 6.5548 mL
50 mM 0.0524 mL 0.2622 mL 0.5244 mL 1.0488 mL 1.311 mL
100 mM 0.0262 mL 0.1311 mL 0.2622 mL 0.5244 mL 0.6555 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
J Nat Prod. 2000 Jun;63(6):857-60.
Characterization of two structural forms of otonecine-type pyrrolizidine alkaloids from Ligularia hodgsonii by NMR spectroscopy.[Pubmed: 10869221]

METHODS AND RESULTS:
Clivorine (1) and Ligularine (2), two hepatotoxic otonecine-type pyrrolizidine alkaloids isolated from Ligularia hodgsonii, an antitussive traditional Chinese medicine, were investigated in CDCl(3) and D(2)O by various NMR techniques to delineate why this type of alkaloid displays uncharacteristic solubility properties by dissolving in both nonpolar organic and aqueous solutions.
CONCLUSIONS:
The results demonstrated that both alkaloids exist in a non-ionized form in CDCl(3), but in an ionized form in D(2)O, suggesting that this unique dual solubility may play a role in the intoxication resultant from consumption of water extracts of herbs, including herbal teas, containing otonecine-type pyrrolizidine alkaloids.
CFN00363Crotafoline38494-87-0351.40C18H25NO6
CFN00378Ligularine34429-54-4381.4C19H27NO7
CFN00408Isatidine15503-86-3367.40C18H25NO7
CFN00418Senecionine N-oxide13268-67-2351.17C18H25NO6
CFN00420Seneciphyllinine90341-45-0375.42C20H25NO6
CFN00421Riddelline23246-96-0349.38C18H23NO6
CFN00469Riddelline N-oxide75056-11-0365.4C18H23NO7
CFN00422Spartioidine520-59-2333.38C18H23NO5
CFN0047818-HydroxyspartioidineN/A349.4C18H23NO6
CFN00424Senkirkine2318-18-5365.42C19H27NO6
Featured Products
Cinnamic acid

Catalog No: CFN99453
CAS No: 140-10-3
Price: $30/20mg
Kukoamine B

Catalog No: CFN93216
CAS No: 164991-67-7
Price: $268/10mg
Isochlorogenic acid C

Catalog No: CFN99120
CAS No: 32451-88-0
Price: $70/20mg
Aloenin A

Catalog No: CFN93235
CAS No: 38412-46-3
Price: $ / mg
Fraxetin

Catalog No: CFN99113
CAS No: 574-84-5
Price: $30/20mg
Timosaponin A3

Catalog No: CFN98151
CAS No: 41059-79-4
Price: $50/20mg
Solasodine

Catalog No: CFN90200
CAS No: 126-17-0
Price: $168/20mg
Oleuropein

Catalog No: CFN98416
CAS No: 32619-42-4
Price: $30/20mg
Gracillin

Catalog No: CFN98537
CAS No: 19083-00-2
Price: $80/20mg
(-)-Gallocatechin

Catalog No: CFN99137
CAS No: 3371-27-5
Price: $128/20mg
Tags: buy Ligularine | Ligularine supplier | purchase Ligularine | Ligularine cost | Ligularine manufacturer | order Ligularine | Ligularine distributor
1 Building, No. 176, CheCheng East Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Copyright© 2011-2023 | ChemFaces all rights reserved | Tel: +86-27-84237683
E-mail:manager@chemfaces.com
payment