Structure Identification: |
Journal of the Agricultural Chemical Society of Japan, 1986, 50(3):809-811. | New Terpenoids, Ganolucidic Acid D, Ganoderic Acid L, Lucidone C and Lucidenic Acid G, from the Fungus Ganoderma lucidum.[Reference: WebLink] | The fruiting body of the fungus Ganoderma lucidum (Reishi) has attracted much attention as a folk medicine, and some of its components have been elucidated. METHODS AND RESULTS: We have also reported several bitter terpenoids and related compounds from the fungus.1~9) The naming of lucidenic acids is a little confused, so we now designate our lucidenic acids D and E2) as Dx and El5 and Kikuchi's7) as D2 and E2, respectively. Recently, we have isolated four new terpenoids, ganolucidic acid D (1), methyl ganoderate L (2a), lucidone C (3) and methyl lucidenate G (4a). Ganolucidic acid D (1) has a allylic alcohol group in the side chain and can the mycelial components10) and terpenoids of the fruiting body. On the other hand, Ganoderic acid L (2), which has a hydroxyl group at C-20, can be a possible precursor of lucidone C (3). CONCLUSIONS: Among the lucidenic acids, lucidenic acid G (4) is unique in having a hydroxyl group at C-26. |
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