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(E)-N-Caffeoylputrescine
(E)-N-Caffeoylputrescine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name (E)-N-Caffeoylputrescine
Price: $388 / 5mg
CAS No.: 29554-26-5
Catalog No.: CFN93323
Molecular Formula: C13H18N2O3
Molecular Weight: 250.29 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Exochorda racemosa
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / $187.6 / In-stock
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: N-Caffeoylputrescine has antioxidant activity.
In vitro:
J Agric Food Chem. 2014 Jan 29;62(4):850-9.
Antioxidant activity of phenolics in leaves of three red pepper (Capsicum annuum) cultivars.[Pubmed: 24087837 ]
The antioxidant properties and phenolic profiles were first investigated in this paper on the leaves of three red pepper cultivars, Blackcuban (BCPL), Hongjinju (HPL), and Yeokgang-hongjanggun (YHPL).
METHODS AND RESULTS:
Of the ethanol extract of the three cultivars, BCPL showed potent antioxidant activities against the 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) and the 2,2-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical. Nine antioxidative compounds from the red pepper leaves were isolated and identified as one polyamine phenolic conjugate, N-caffeoylputrescine ((E)-N-Caffeoylputrescine,1); three chlorogenic acid derivatives, 5-O-caffeoylquinic acid (2), 5-O-caffeoylquinic acid methyl ester (4), and 5-O-caffeoylquinic acid butyl ester (9); one anthocyanin, delphinidin-3-[4-trans-coumaroyl-l-rhamnosyl(1→6)glucopyranoside]-5-O-glucopyranoside (3); and four flavone glycosides, luteolin-7-O-apiofuranosyl(1→2)glucopyranoside (5), luteolin-7-O-glucopyranoside (6), apigenin 7-O-apiofuranosyl(1→2)glucopyranoside (7), apigenin-7-O-glucopyranoside (8).
CONCLUSIONS:
1 and 3 had the greatest potential for radical-scavenging activity and HepG2 cells protecting effect against oxidative stress. BCPL exhibited the highest content of 1 and 3. Of the three cultivars BCPL may be considered a good source of antioxidants.
(E)-N-Caffeoylputrescine Description
Source: The herbs of Exochorda racemosa
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

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IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.9954 mL 19.9768 mL 39.9537 mL 79.9073 mL 99.8841 mL
5 mM 0.7991 mL 3.9954 mL 7.9907 mL 15.9815 mL 19.9768 mL
10 mM 0.3995 mL 1.9977 mL 3.9954 mL 7.9907 mL 9.9884 mL
50 mM 0.0799 mL 0.3995 mL 0.7991 mL 1.5981 mL 1.9977 mL
100 mM 0.04 mL 0.1998 mL 0.3995 mL 0.7991 mL 0.9988 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Phytochemistry (Oxford), 1996, 42(2):389-396.
Changes in the accumulation of soluble and cell wall-bound phenolics in elicitor-treated cell suspension cultures and fungus-infected leaves of Solanum tuberosum.[Reference: WebLink]
Cell suspension cultures of potato (Solanum tuberosum cv. Datura) treated with an elicitor preparation from Phytophthora infestans and potato leaves infected with the same fungus were used to study changes in the accumulation patterns of soluble and cell wall-bound phenolics.
METHODS AND RESULTS:
The compounds were identified by chromatographic comparison with authentic substances and by spectroscopic methods (FAB mass spectrometry, 1H and 13C NMR). The soluble phenolics were 4-O-β-glucopyranosylhydroquinone (arbutin), 4-O-β-glucopyranosylbenzoate, 3-methoxy-4-O-β-glucopyranosylbenzoate (vanillate glucoside), N-(E)-caffeoylputrescine((E)-N-Caffeoylputrescine), 2-O-β-glucopyranosylbenzoate (salicylate glucoside), N-(E)-feruloylputrescine, and N-(E)-feruloylaspartate. The cell wall-bound phenolics were 4-hydroxybenzoate, 4-hydroxybenzaldehyde, 3-methoxy-4-hydroxybenzaldehyde (vanillin), 4-(E)-coumarate, (E)-ferulate, N-4-(E)-coumaroyltyramine, and N-(E)-feruloyltyramine.
CONCLUSIONS:
The most prominent phenolics showing elicitor- or fungus-induced increases in accumulation rates were the soluble putrescine amides and cell wall-bound 4-hydroxybenzaldehyde and tyramine amides. In addition, there was a secretion of large amounts of coumaroyltyramine into the cell culture medium.
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