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Norjuziphine
Norjuziphine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Norjuziphine
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CAS No.: 74119-87-2
Catalog No.: CFN92409
Molecular Formula: C17H19NO3
Molecular Weight: 285.3 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Cryst.
Source: The tubers of Corydalis incisa
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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  • The University of Newcastle (Australia)
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Norjuziphine has antiplatelet aggregation activity.
In vitro:
Planta Med. 2001 Jul;67(5):423-7.
A new tetrahydroprotoberberine N-oxide alkaloid and anti-platelet aggregation constituents of Corydalis tashiroi.[Pubmed: 11488455]

METHODS AND RESULTS:
A new tetrahydroprotoberberine N-oxide alkaloid, (-)-cis-isocorypalmine N-oxide (1), together with two known compounds, 6-methoxydihydrosanguinarine (2) and Norjuziphine (3), were isolated in continuing studies of the entire Formosan Corydalis tashiroi plant.
CONCLUSIONS:
The structures of these three compounds were determined through spectral analyses. In addition, compounds 1, 2, 3 and the seven alkaloids previously reported: (-)-cis-corydalmine N-oxide, (-)-trans-corydalmine N-oxide, (-)-trans-isocorypalmine N-oxide, scoulerine, protopine, oxysanguinarine and corydalmine, were found to possess antiplatelet aggregation activity.
Norjuziphine Description
Source: The tubers of Corydalis incisa
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.5051 mL 17.5254 mL 35.0508 mL 70.1016 mL 87.6271 mL
5 mM 0.701 mL 3.5051 mL 7.0102 mL 14.0203 mL 17.5254 mL
10 mM 0.3505 mL 1.7525 mL 3.5051 mL 7.0102 mL 8.7627 mL
50 mM 0.0701 mL 0.3505 mL 0.701 mL 1.402 mL 1.7525 mL
100 mM 0.0351 mL 0.1753 mL 0.3505 mL 0.701 mL 0.8763 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
J Nat Prod. 1984 May-Jun;47(3):459-64.
Additional alkaloids of Pachygone ovata.[Pubmed: 6481360]

METHODS AND RESULTS:
Pachygone ovata (Menispermaceae), indigenous to the sandy seashores of southern India, is a woody climber whose fruits have been used as a rodenticide and fish poison. Chromatography of the extract of the roots resulted in the reisolation of the alkaloids liriodenine, coclaurine, trilobine (1), and magnoflorine and the isolation of stepholidine, coreximine, isoboldine, Norjuziphine, and nortrilobine (2).
CONCLUSIONS:
Nortrilobine (2) is a new dibenzo-p-dioxin bisbenzylisoquinoline alkaloid whose structure was established by a consideration of spectral data and conversion to isotrilobine (3).
CFN95588N-MethyldehydrococlaurineN/A298.4C18H20NO3+
CFN96626Tetrahydropapaverine hydrochloride6429-04-5379.88C20H26ClNO4
CFN93230Magnocurarine6801-40-7314.4C19H24NO3
CFN92409Norjuziphine74119-87-2285.3C17H19NO3
CFN97013Oblongine60008-01-7314.4 C19H24NO3
CFN95589N-DemethylfordianosideN/A448.5C23H30NO8+
CFN98767Reticuline485-19-8329.4 C19H23NO4
CFN95013(R)-Reticuline3968-19-2329.4C19H23NO4
CFN95542Tembetarine18446-73-6344.4C20H26NO4
CFN98769Coclaurine486-39-5285.3 C17H19NO3
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