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Oxohydrastinine
Oxohydrastinine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Oxohydrastinine
Price:
CAS No.: 552-29-4
Catalog No.: CFN92334
Molecular Formula: C11H11NO3
Molecular Weight: 205.2 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Thalictrum aquilegifolium
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Oxohydrastinine shows certain antibacterial activity in vitro.
Targets: Antifection
In vitro:
J Med Plants Res.2011 Jan; 5.
Seven alkaloids and their antibacterial activity from Hypecoum erectum L.[Reference: WebLink]

METHODS AND RESULTS:
From the aerial part of Hypecoum erectum L., seven alkaloids, Protopine (1), Cryptopine (2), Allocryptopine (3), Hypecorinine (4), (-)-N-Methylcanadine (5), Oxohydrastinine (6) and N-Methylcorydaldine (7) were isolated. The structures of the seven compounds were established by 1 H-NMR, 13 C-NMR, DEPT and ESI-MS analyses. Compounds 2, 5 and 7 were obtained from this plant for the first time. The antibacterial activities were investigated against six bacteria (3 gram-positive and 3 gram-negative) by disc diffusion method followed by the minimal inhibitory concentration (MIC) which was determined using a two fold serial dilution assay for the compound which have inhibitory effect.
CONCLUSIONS:
In vitro antimicrobial activities assay indicated that some compounds showed promising activities. To the best of our knowledge, this is the first report on the antimicrobial properties of these alkaloids from this plant.
Oxohydrastinine Description
Source: The herbs of Thalictrum aquilegifolium
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.8733 mL 24.3665 mL 48.7329 mL 97.4659 mL 121.8324 mL
5 mM 0.9747 mL 4.8733 mL 9.7466 mL 19.4932 mL 24.3665 mL
10 mM 0.4873 mL 2.4366 mL 4.8733 mL 9.7466 mL 12.1832 mL
50 mM 0.0975 mL 0.4873 mL 0.9747 mL 1.9493 mL 2.4366 mL
100 mM 0.0487 mL 0.2437 mL 0.4873 mL 0.9747 mL 1.2183 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Phytochemistry.1999 Jan 26;50(2):339–343.
Five alkaloids from Hypecoum leptocarpum.[Reference: WebLink]

METHODS AND RESULTS:
Five new alkaloids, leptocarpinine, leptopine, leptopinine, leptopidine and leptopidinine were isolated, together with protopine, isohyperectine and Oxohydrastinine, from Hypecoum leptocarpum. The structures were elucidated by spectral evidence.
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Cinnamyl alcohol

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Ellagic acid

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Price: $ / mg
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