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Petasinine
Petasinine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Petasinine
Price:
CAS No.: 70474-33-8
Catalog No.: CFN00276
Molecular Formula: C13H21NO3
Molecular Weight: 239.31 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Petasites japonicus
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Reference standards.
Petasinine Description
Source: The herbs of Petasites japonicus
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.1787 mL 20.8934 mL 41.7868 mL 83.5736 mL 104.467 mL
5 mM 0.8357 mL 4.1787 mL 8.3574 mL 16.7147 mL 20.8934 mL
10 mM 0.4179 mL 2.0893 mL 4.1787 mL 8.3574 mL 10.4467 mL
50 mM 0.0836 mL 0.4179 mL 0.8357 mL 1.6715 mL 2.0893 mL
100 mM 0.0418 mL 0.2089 mL 0.4179 mL 0.8357 mL 1.0447 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Scientia Pharmaceutica 2002:Vol 70, No 4
Pyrrolizidine Alkaloide in Petasites fragrans[Reference: WebLink]

METHODS AND RESULTS:
Three pyrrolizidine alkaloids, senkirkine, Petasinine and 7-angeloylretronecine or anisomer have been isolated from Petasites fragrans. Their structures were elucidated by spectroscopic methods.
CFN00277Petasinoside70474-34-9531.60C28H37NO9
CFN00278Thesinine488-02-8287.36C17H21NO3
CFN00282Ehretinine76231-29-3275.35C16H21NO3
CFN00283Indicine480-82-0299.36C15H25NO5
CFN00284Indicine N-oxide41708-76-3315.37C15H25NO6
CFN00285Intermedine10285-06-0299.36C15H25NO5
CFN00459Intermedine N-oxide95462-14-9315.4C15H25NO6
CFN002867-Acetylintermedine74243-01-9341.40C17H27NO6
CFN005187-O-Acetylintermedine N-oxide685132-59-6357.4C17H27NO7
CFN00287Lycopsamine10285-07-1299.37C15H25NO5
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