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Physapruin A
Physapruin A
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Physapruin A
Price:
CAS No.: 155178-03-3
Catalog No.: CFN89294
Molecular Formula: C28H38O7
Molecular Weight: 486.60 g/mol
Purity: >=98%
Type of Compound: Steroids
Physical Desc.: Powder
Source: The fresh aerial parts of Physalis pruinosa.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Physapruin A is a natural product from Physalis pruinosa.
Physapruin A Description
Source: The fresh aerial parts of Physalis pruinosa.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0551 mL 10.2754 mL 20.5508 mL 41.1015 mL 51.3769 mL
5 mM 0.411 mL 2.0551 mL 4.1102 mL 8.2203 mL 10.2754 mL
10 mM 0.2055 mL 1.0275 mL 2.0551 mL 4.1102 mL 5.1377 mL
50 mM 0.0411 mL 0.2055 mL 0.411 mL 0.822 mL 1.0275 mL
100 mM 0.0206 mL 0.1028 mL 0.2055 mL 0.411 mL 0.5138 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chemical & Pharmaceutical Bulletin, 1993, 41:1873-1875.
Physapruins A and B, Two New Withanolides from Physalis pruinosa BAILEY.[Reference: WebLink]
Two new withanolides, Physapruin A and physapruin B, were isolated from the methanolic extract of the fresh aerial parts of Physalis pruinosa (Solanaceae), and their structures have been determined to be 4β, 14α, 17β, 20β-tetrahydroxy-1-oxo-20S, 22R-witha-2,5,24-trienolide (1) and 6β-acetoxy-5α-butoxy-14α-17β-20β-trihydroxy-1-oxo-20S, 22R-witha-2,24-dienolide (2) on the basis of spectral evidence.
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Dehydroabietic acid

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Uridine

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Glycyrrhetinic acid

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Isochlorogenic acid A

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Coronaridine

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Pectolinarigenin

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(20S)-Protopanaxdiol

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