Science | Nature | Cell | View More
Natural Products
Rhaponticin 6''-O-gallate
Rhaponticin 6''-O-gallate
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Rhaponticin 6''-O-gallate
Price: $268 / 5mg
CAS No.: 94356-23-7
Catalog No.: CFN91099
Molecular Formula: C28H28O13
Molecular Weight: 572.51 g/mol
Purity: >95%
Type of Compound: Miscellaneous
Physical Desc.: Powder
Source: The roots of Rumex obtusifolius L.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $308.2 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • University of Leipzig (Germany)
  • Centrum Menselijke Erfelijkheid (Belgium)
  • University of Hull (United Kingdom)
  • National Chung Hsing University (Taiwan)
  • VIB Department of Plant Systems... (Belgium)
  • Semmelweis Unicersity (Hungary)
  • Seoul National University (Korea)
  • The University of Newcastle (Australia)
  • University of Mysore (India)
  • Universidad de La Salle (Mexico)
  • Rio de Janeiro State University (Brazil)
  • More...
Package
Featured Products
3,4,5-Tricaffeoylquinic acid

Catalog No: CFN90238
CAS No: 86632-03-3
Price: $318/5mg
Piceatannol

Catalog No: CFN99024
CAS No: 10083-24-6
Price: $40/20mg
Alloimperatorin

Catalog No: CFN93037
CAS No: 642-05-7
Price: $298/10mg
Magnolin

Catalog No: CFN98391
CAS No: 31008-18-1
Price: $70/20mg
Magnolol

Catalog No: CFN98872
CAS No: 528-43-8
Price: $30/20mg
Ginsenoside Rc

Catalog No: CFN99973
CAS No: 11021-14-0
Price: $70/20mg
Tracheloside

Catalog No: CFN90597
CAS No: 33464-71-0
Price: $50/20mg
Kurarinone

Catalog No: CFN92003
CAS No: 34981-26-5
Price: $118/20mg
Myrcene

Catalog No: CFN70046
CAS No: 123-35-3
Price: $30/20mg
Notopterol

Catalog No: CFN98563
CAS No: 88206-46-6
Price: $80/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Rhaponticin 6''-O-gallate showed inhibitory activity of NO production in lipopolysaccharide-activated macrophages, (IC50 = 11-69 microM).
Targets: NO
In vitro:
Bioorg Med Chem Lett. 2000 Feb 21;10(4):323-7.
Effects of stilbene constituents from rhubarb on nitric oxide production in lipopolysaccharide-activated macrophages.[Pubmed: 10714491 ]

METHODS AND RESULTS:
Two new anthraquinone glucosides [chrysophanol 8-O-beta-D-(6'-galloyl)-glucopyranoside, aloe-emodin 1-O-beta-D-glucopyranoside] together with various known stilbenes and their glucosides, anthraquinone glucosides, and a naphthalene glucoside were isolated from the rhizome of Rheum undulatum L. Three stilbenes (rhapontigenin, piceatannol, resveratrol), a naphthalene glucoside (torachrysone 8-O-beta-D-glucopyranoside), and two stilbene glucoside gallates (rhaponticin 2''-O-gallate, Rhaponticin 6''-O-gallate) showed inhibitory activity of NO production in lipopolysaccharide-activated macrophages, (IC50 = 11-69 microM).
CONCLUSIONS:
The oxygen functions (-OH,-OCH3) at the benzene ring were found to be essential to show the activity. Whereas, the glucoside moiety reduced the activity, while the alpha,beta-double bond did not affect the activity. Furthermore, the active stilbenes (rhapontigenin, piceatannol, resveratrol) inhibited iNOS induction.
Rhaponticin 6''-O-gallate Description
Source: The roots of Rumex obtusifolius L.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Quercetin-3'-glucoside

Catalog No: CFN95271
CAS No: 19254-30-9
Price: $318/10mg
Glaucoside A

Catalog No: CFN95299
CAS No: 81474-91-1
Price: $318/5mg
Acacetin 7-[rhamnosyl-(1->2)-galac...

Catalog No: CFN95358
CAS No: 38722-95-1
Price: $318/10mg
Oleuroside

Catalog No: CFN95099
CAS No: 116383-31-4
Price: $288/20mg
Diosmin Impurity 5

Catalog No: CFN95311
CAS No: 122087-66-5
Price: $318/10mg
Rhamnocitrin 3-glucoside

Catalog No: CFN95134
CAS No: 41545-37-3
Price: $318/10mg
Dactylorhin A

Catalog No: CFN95032
CAS No: 256459-34-4
Price: $238/20mg
Isorubrofusarin 10-gentiobioside

Catalog No: CFN95119
CAS No: 200127-93-1
Price: $338/10mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.7467 mL 8.7335 mL 17.4669 mL 34.9339 mL 43.6674 mL
5 mM 0.3493 mL 1.7467 mL 3.4934 mL 6.9868 mL 8.7335 mL
10 mM 0.1747 mL 0.8733 mL 1.7467 mL 3.4934 mL 4.3667 mL
50 mM 0.0349 mL 0.1747 mL 0.3493 mL 0.6987 mL 0.8733 mL
100 mM 0.0175 mL 0.0873 mL 0.1747 mL 0.3493 mL 0.4367 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
3,4,5-Tricaffeoylquinic acid

Catalog No: CFN90238
CAS No: 86632-03-3
Price: $318/5mg
Piceatannol

Catalog No: CFN99024
CAS No: 10083-24-6
Price: $40/20mg
Alloimperatorin

Catalog No: CFN93037
CAS No: 642-05-7
Price: $298/10mg
Magnolin

Catalog No: CFN98391
CAS No: 31008-18-1
Price: $70/20mg
Magnolol

Catalog No: CFN98872
CAS No: 528-43-8
Price: $30/20mg
Ginsenoside Rc

Catalog No: CFN99973
CAS No: 11021-14-0
Price: $70/20mg
Tracheloside

Catalog No: CFN90597
CAS No: 33464-71-0
Price: $50/20mg
Kurarinone

Catalog No: CFN92003
CAS No: 34981-26-5
Price: $118/20mg
Myrcene

Catalog No: CFN70046
CAS No: 123-35-3
Price: $30/20mg
Notopterol

Catalog No: CFN98563
CAS No: 88206-46-6
Price: $80/20mg
Tags: buy Rhaponticin 6''-O-gallate | Rhaponticin 6''-O-gallate supplier | purchase Rhaponticin 6''-O-gallate | Rhaponticin 6''-O-gallate cost | Rhaponticin 6''-O-gallate manufacturer | order Rhaponticin 6''-O-gallate | Rhaponticin 6''-O-gallate distributor