Schizanrin L | CAS:874472-16-9 | Manufacturer ChemFaces

Schizanrin L

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Description:

Schizanrin L is a natural product from Kadsura coccinea.

In vitro:

Planta Med. 2005 Jul;71(7):646-53.

Antihepatitis activity (anti-HBsAg and anti-HBeAg) of C19 homolignans and six novel C18 dibenzocyclooctadiene lignans from Kadsura japonica.[Pubmed: 16041651 ]

METHODS AND RESULTS:
Bioassay-directed fractionation of the EtOAc extract of Kadsura japonica has led to the isolation of six new C18 dibenzocyclooctadiene lignans, schizanrin I, schizanrin J, schizanrin K, Schizanrin L, schizanrin M, schizanrin N, along with four known C19 homolignans, taiwanschirins A, B, C, and heteroclitin F. The elucidations of the new structures were based on spectral analysis.
CONCLUSIONS:
Bioassay evaluation against human type B hepatitis revealed that taiwanschirins A and B showed strong activity for anti-HBsAg and a medium effect for anti-HBeAg at 25 microg/mL (12.9 and 11.9 microM for taiwanschirins A and B, respectively).

Schizanrin L Description

Source:	The herbs of Kadsura coccinea
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Schizanrin L
Price:
CAS No.:	874472-16-9
Catalog No.:	CFN92714
Molecular Formula:	C₃₁H₃₆O₈
Molecular Weight:	536.6 g/mol
Purity:	>=98%
Type of Compound:	Lignans
Physical Desc.:	Cryst.
Source:	The herbs of Kadsura coccinea
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Lignans Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.8636 mL	9.3179 mL	18.6359 mL	37.2717 mL	46.5896 mL
5 mM	0.3727 mL	1.8636 mL	3.7272 mL	7.4543 mL	9.3179 mL
10 mM	0.1864 mL	0.9318 mL	1.8636 mL	3.7272 mL	4.659 mL
50 mM	0.0373 mL	0.1864 mL	0.3727 mL	0.7454 mL	0.9318 mL
100 mM	0.0186 mL	0.0932 mL	0.1864 mL	0.3727 mL	0.4659 mL

CFN92114	Interiotherin A	181701-06-4	504.5	C₂₉H₂₈O₈
CFN92729	O-Acetylschisantherin L	149998-51-6	540.6	C₂₉H₃₂O₁₀
CFN80191	Heteroclitin D	140369-76-2	482.19	C₂₇H₃₀O₈
CFN91160	Gomisin U	135095-46-4	418.5	C₂₃H₃₀O₇
CFN92725	Kadsulignan N	163564-58-7	430.5	C₂₄H₃₀O₇
CFN92721	Kadsulignan L	163660-06-8	414.5	C₂₃H₂₆O₇
CFN92714	Schizanrin L	874472-16-9	536.6	C₃₁H₃₆O₈
CFN97333	Isogomisin O	83916-76-1	416.5	C₂₃H₂₈O₇
CFN92726	Heteroclitin C	140460-42-0	498.6	C₂₈H₃₄O₈
CFN92842	Heteroclitin B	140461-47-8	498.6	C₂₈H₃₄O₈