Sennoside A1 | CAS:66575-30-2 | Manufacturer ChemFaces

Sennoside A1

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Sennoside A1 Description

Source:	The leaves of Cassia angustifolia.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Journal of Separation Science, 2015, 38(20):3502-3507.

Simultaneous separation of three isomeric sennosides from senna leaf (Cassia acutifolia) using counter-current chromatography.[Reference: WebLink]

Senna leaf is widely consumed as tea to treat constipation or to aid in weight loss. Sennoside A, Sennoside A1 , and Sennoside B are dirheinanthrone glucosides that are abundant and the bioactive constituents in the plant. They are isomers that refer to the (R*R*), (S*S*), and (R*S*) forms of protons on C-10 and C-10' centers and it is difficult to refine them individually due to their structural similarities.
METHODS AND RESULTS:
The new separation method using counter-current chromatography successfully purified sennoside A, A1 , and B from senna leaf (Cassia acutifolia) while reversed-phase medium-pressure liquid chromatography yielded sennoside A only. n-Butanol/isopropanol/water (5:1:6, v/v/v) was selected as the solvent system for counter-current chromatography operation, and the partition coefficients were carefully determined by adding different concentrations of formic acid.
CONCLUSIONS:
High-resolution mass spectrometry and NMR spectroscopy were performed to verify the chemical properties of the compounds.

Product Name	Sennoside A1
Price:
CAS No.:	66575-30-2
Catalog No.:	CFN70436
Molecular Formula:	C₄₂H₃₈O₂₀
Molecular Weight:	862.8 g/mol
Purity:	>=98%
Type of Compound:	Anthraquinones
Physical Desc.:	Powder
Source:	The leaves of Cassia angustifolia.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Download:	COA MSDS
Similar structural:	Comparison
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Anthraquinones Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.159 mL	5.7951 mL	11.5902 mL	23.1803 mL	28.9754 mL
5 mM	0.2318 mL	1.159 mL	2.318 mL	4.6361 mL	5.7951 mL
10 mM	0.1159 mL	0.5795 mL	1.159 mL	2.318 mL	2.8975 mL
50 mM	0.0232 mL	0.1159 mL	0.2318 mL	0.4636 mL	0.5795 mL
100 mM	0.0116 mL	0.058 mL	0.1159 mL	0.2318 mL	0.2898 mL

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CFN00005	AAL Toxin TE1	176590-37-7	531.68	C₂₇H₄₉NO₉
CFN95509	8-epi-Confertin	110115-60-1	248.3	C₁₅H₂₀O₃
CFN98356	Phlorigidoside B	288248-46-4	464.4	C₁₉H₂₈O₁₃