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Simiarenone
Simiarenone
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Simiarenone
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CAS No.: 2318-78-7
Catalog No.: CFN98239
Molecular Formula: C30H48O
Molecular Weight: 424.7 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The herbs of Euphorbia lathyris L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Reference standards.
Simiarenone Description
Source: The herbs of Euphorbia lathyris L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.3546 mL 11.773 mL 23.546 mL 47.0921 mL 58.8651 mL
5 mM 0.4709 mL 2.3546 mL 4.7092 mL 9.4184 mL 11.773 mL
10 mM 0.2355 mL 1.1773 mL 2.3546 mL 4.7092 mL 5.8865 mL
50 mM 0.0471 mL 0.2355 mL 0.4709 mL 0.9418 mL 1.1773 mL
100 mM 0.0235 mL 0.1177 mL 0.2355 mL 0.4709 mL 0.5887 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Zhongguo Zhong Yao Za Zhi. 2009 Jan;34(2):183-5.
Studies on chemical constituents from roots of Polygonum amplexicaule.[Pubmed: 19385182]
To investigate the chemical constituents in the roots of Polygonum amplexicaule var. sinense.
METHODS AND RESULTS:
The compounds were isolated by column chromatography on silica gel and Sephadex LH-20. The structures were identified by means of IR, 1H-NMR, 13C-NMR and MS analyses. Eight compounds were isolated and identified as friedelin (1), beta-sitosterol (2), Simiarenone (3), angelicin (4), psoralen (5), palmitic acid (6), (-)-epicatechin (7), and quercetin (8), respectively.
CONCLUSIONS:
All compounds were isolated from this species for the first time and compounds 1, 3-6 were obtained from this genus for the first time.
CFN89172Filicenol B145103-37-3426.72C30H50O
CFN89179Filic-3-en-25-al147850-78-0424.71C30H48O
CFN9779324-Norhopa-4(23),22(29)-diene-3beta,6beta-diol194613-74-6426.68C29H46O2
CFN99261Alstonic acid A1159579-44-8456.7 C30H48O3
CFN99262Alstonic acid B1159579-45-9454.7 C30H46O3
CFN97985Hopane-3beta,22-diol22149-65-1444.7C30H52O2
CFN98222Zeorin22570-53-2444.7 C30H52O2
CFN97469Sorghumol90582-44-8426.7 C30H50O
CFN97470Sorghumol acetate90582-47-1468.8 C32H52O2
CFN99393Rubiarbonol B130288-60-7458.7 C30H50O3
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