Sissotrin | CAS:5928-26-7 | Manufacturer ChemFaces

Sissotrin

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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $268 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Description:

Sissotrin can impair glucose tolerance.

In vivo:

Phytother Res. 2008 Apr;22(4):539-43.

The opposing effects of the flavonoids isoquercitrin and sissotrin, isolated from Pterospartum tridentatum, on oral glucose tolerance in rats.[Pubmed: 18338765]

METHODS AND RESULTS:
The isoflavone Sissotrin and the flavonol derivative, isoquercitrin, were selected for the oral glucose tolerance test. Isoquercitrin (100 mg/kg) showed time-dependent antihyperglycaemic activity by delaying the post-oral glucose load glycaemic peak at 30 min, as did the sodium-dependent glucose transporter inhibitor phloridzin (100 mg/kg). In contrast, Sissotrin (100 mg/kg) showed an opposite effect, impairing glucose tolerance.
CONCLUSIONS:
In conclusion, these preliminary results indicate that the effect of the extract on blood glucose may be either antihyperglycaemic or hyperglycaemic. Additionally, as far as is known, these are the first in vivo results on the acute antihyperglycaemic potential of isoquercitrin.

Sissotrin Description

Source:	The herbs of Trifolium pratense L.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Sissotrin
Price:	$268 / 5mg
CAS No.:	5928-26-7
Catalog No.:	CFN97005
Molecular Formula:	C₂₂H₂₂O₁₀
Molecular Weight:	446.4 g/mol
Purity:	>=98%
Type of Compound:	Flavonoids
Physical Desc.:	Yellow powder
Source:	The herbs of Trifolium pratense L.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Anti-insulin Compound Library Flavonoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.2401 mL	11.2007 mL	22.4014 mL	44.8029 mL	56.0036 mL
5 mM	0.448 mL	2.2401 mL	4.4803 mL	8.9606 mL	11.2007 mL
10 mM	0.224 mL	1.1201 mL	2.2401 mL	4.4803 mL	5.6004 mL
50 mM	0.0448 mL	0.224 mL	0.448 mL	0.8961 mL	1.1201 mL
100 mM	0.0224 mL	0.112 mL	0.224 mL	0.448 mL	0.56 mL

CFN97943	Griffithazanone A	240122-30-9	257.2	C₁₄H₁₁NO₄
CFN99249	Pseudolaric acid D	115028-67-6	318.5	C₂₀H₃₀O₃
CFN96181	Pelirine	30435-26-8	354.5	C₂₁H₂₆N₂O₃
CFN92130	Laurycolactone A	85643-76-1	318.4	C₁₈H₂₂O₅