| Structure Identification: |
| Planta Med 2015; 81 - PM_126 | | Constituents of the fruits of Vaccinium uliginosum (bog bilberry)[Reference: WebLink] | As a part of our ongoing project to search novel secondary metabolites from medicinal plants, we chose the fruits of V. uliginosum for detailed phytochemical study.
METHODS AND RESULTS:
Repeated chromatography of freeze-dried extract of berries led to isolation of eleven compounds, comprising an anthocyanin, six flavonoids, two phenyl propanoids, and two iridoids. The isolates were identified as cyanidin-3-O-β-D-glucopyranoside (1), quercetin (2), hyperoside (quercetin-3-O-β-D-galactopyranoside) (3), quercetin-3-O-α-L-arabinopyranoside (4), myricetin (5), myricetin-3-O-β-D-galactopyranoside (6), syringetin-3-O-β-D-galactopyranoside (7), methylchlorogenate (8), chlorogenic acid (9), loganic acid (10), and 6,7-dihydromonotropein methyl ester (Splendoside) (11) by physical (mp, [α]D) and spectroscopic data (1H NMR, 13C NMR, 2D NMR, and MS) measurement and by comparison with published values.
CONCLUSIONS:
Although loganic acid (10) and 6,7-dihydromonotropein methyl ester (Splendoside) (11) were isolated from other Vaccinium species, they have not been reported from V. uliginosum to date. |
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