Structure Identification: |
Zhongguo Zhong Yao Za Zhi. 2012 May;37(9):1249-53. | Chemical constituents of Dolomiaea souliei.[Pubmed: 22803370] | To study the chemical constituents of Dolomiaea souliei.
METHODS AND RESULTS:
Various chromatographic techniques were adopted to separate the constituents, and the spectrum analysis was made to identify their structures.
Seventeen compounds were isolated and identified as: dehydrocostus lactone (1), costunolide (2), mokko lactone (3), santamarine(4), reynosin (5), 4alpha-hydroxy-4beta-methyldihydrocostol (6), Sulfocostunolide A (7), beta-costic acid (8), beta-cyclocostunolide (9), vladinol A (10), ursolic acid (11), betulinic acid (12), betulin (13), dibutyl terephthalate (14), dibutyl phthalate (15), uridine (16), and emodin (17).
CONCLUSIONS:
Compounds 6-9 and 12-17 were obtained from this genus for the first time, and compound 11 was obtained from this plant for the first time. | Chem Pharm Bull (Tokyo). 2008 Jun;56(6):864-5. | Sulfonated guaianolides from Saussurea lappa.[Pubmed: 18520098] |
METHODS AND RESULTS:
Two new guaiane-type sesquiterpene lactones with an unusual sulfonic acid group, Sulfocostunolide A (1) and sulfocostunolide B (2), were isolated from the roots of Saussurea lappa.
Their structures were elucidated on the basis of extensive spectroscopic analysis. |
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