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Sulfocostunolide A
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Sulfocostunolide A
Price:
CAS No.: 1016983-51-9
Catalog No.: CFN99030
Molecular Formula: C15H20O5S
Molecular Weight: 312.4 g/mol
Purity: >=98%
Type of Compound: Sesquiterpenoids
Physical Desc.: Oil
Source: The root of Saussurea lappa
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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10 mM * 1 mL in DMSO / Inquiry / In-stock
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Description: Reference standards.
Sulfocostunolide A Description
Source: The root of Saussurea lappa
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.201 mL 16.0051 mL 32.0102 mL 64.0205 mL 80.0256 mL
5 mM 0.6402 mL 3.201 mL 6.402 mL 12.8041 mL 16.0051 mL
10 mM 0.3201 mL 1.6005 mL 3.201 mL 6.402 mL 8.0026 mL
50 mM 0.064 mL 0.3201 mL 0.6402 mL 1.2804 mL 1.6005 mL
100 mM 0.032 mL 0.1601 mL 0.3201 mL 0.6402 mL 0.8003 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Zhongguo Zhong Yao Za Zhi. 2012 May;37(9):1249-53.
Chemical constituents of Dolomiaea souliei.[Pubmed: 22803370]
To study the chemical constituents of Dolomiaea souliei.
METHODS AND RESULTS:
Various chromatographic techniques were adopted to separate the constituents, and the spectrum analysis was made to identify their structures. Seventeen compounds were isolated and identified as: dehydrocostus lactone (1), costunolide (2), mokko lactone (3), santamarine(4), reynosin (5), 4alpha-hydroxy-4beta-methyldihydrocostol (6), Sulfocostunolide A (7), beta-costic acid (8), beta-cyclocostunolide (9), vladinol A (10), ursolic acid (11), betulinic acid (12), betulin (13), dibutyl terephthalate (14), dibutyl phthalate (15), uridine (16), and emodin (17).
CONCLUSIONS:
Compounds 6-9 and 12-17 were obtained from this genus for the first time, and compound 11 was obtained from this plant for the first time.
Chem Pharm Bull (Tokyo). 2008 Jun;56(6):864-5.
Sulfonated guaianolides from Saussurea lappa.[Pubmed: 18520098]

METHODS AND RESULTS:
Two new guaiane-type sesquiterpene lactones with an unusual sulfonic acid group, Sulfocostunolide A (1) and sulfocostunolide B (2), were isolated from the roots of Saussurea lappa. Their structures were elucidated on the basis of extensive spectroscopic analysis.
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Polyporenic acid C

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