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Taiwanhomoflavone B
Taiwanhomoflavone B
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Taiwanhomoflavone B
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CAS No.: 509077-91-2
Catalog No.: CFN98808
Molecular Formula: C32H24O10
Molecular Weight: 568.5 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Yellow powder
Source: The barks of Cephalotaxus fortunei
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Taiwanhomoflavone B is cytotoxic with ED(50) values of 3.8 and 3.5 microg/ml, against KB oral epidermoid carcinoma and Hepa-3B hepatoma cells, respectively.
Taiwanhomoflavone B Description
Source: The barks of Cephalotaxus fortunei
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.759 mL 8.7951 mL 17.5901 mL 35.1803 mL 43.9754 mL
5 mM 0.3518 mL 1.759 mL 3.518 mL 7.0361 mL 8.7951 mL
10 mM 0.1759 mL 0.8795 mL 1.759 mL 3.518 mL 4.3975 mL
50 mM 0.0352 mL 0.1759 mL 0.3518 mL 0.7036 mL 0.8795 mL
100 mM 0.0176 mL 0.088 mL 0.1759 mL 0.3518 mL 0.4398 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chem Pharm Bull (Tokyo). 2002 Dec;50(12):1607-8.
A novel cytotoxic C-methylated biflavone, taiwanhomoflavone-B from the twigs of Cephalotaxus wilsoniana.[Pubmed: 12499600 ]

METHODS AND RESULTS:
A novel C-methylated biflavone, Taiwanhomoflavone B (1), together with known compounds, 7,4',7"-tri-O-methylamentoflavone, 6-C-methylnaringenin and apigenin-7-O-beta-glucoside were isolated from an ethanolic extract of Cephalotaxus wilsoniana. The structure of Taiwanhomoflavone B was elucidated on the basis of spectroscopic analysis.
CONCLUSIONS:
Taiwanhomoflavone B is cytotoxic with ED(50) values of 3.8 and 3.5 microg/ml, against KB oral epidermoid carcinoma and Hepa-3B hepatoma cells, respectively.
CFN92007Hinokiflavone19202-36-9538.5C30H18O10
CFN91949Neocryptomerin20931-36-6552.48C31H20O10
CFN963902,3-Dihydrohinokiflavone34292-87-0540.5C30H20O10
CFN98808Taiwanhomoflavone B509077-91-2568.5 C32H24O10
CFN91946Imbricataflavone A133336-96-6580.54C33H24O10
CFN971572,3,2'',3''-Tetrahydroochnaflavone678138-59-5542.5 C30H22O10
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