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Thalifoline
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Product Name Thalifoline
Price:
CAS No.: 21796-15-6
Catalog No.: CFN92336
Molecular Formula: C11H13NO3
Molecular Weight: 207.2 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Thalictrum aquilegifolium
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Thalifoline shows antifungal activity, with 100 ug against Fusarium oxysporum f. sp. lycopersici.
Targets: Antifection
In vitro:
Phytochemistry Letters, 2011 , 4 (1) :22-5.
Monophyllidin, a new alkaloid L-proline derivative from Zanthoxylum monophyllum[Reference: WebLink]

METHODS AND RESULTS:
A new L-proline derivative, monophyllidin (1), together with four known compounds, Thalifoline (2), berberine (3), jathrorrhizine (4) and 3β-glucositosterol (5) has been isolated from the bark of Zanthoxylum monophyllum. The structure of compound 1 was elucidated on the basis of extensive spectroscopic data analysis. Characterization of compounds 2–5 was based on spectral analysis and comparison with reported data.
CONCLUSIONS:
Compound 3 showed antibacterial activity against the five bacterial strains used, while 1, 4 and 5 presented only antibacterial activity against Enterococcus faecalis. Compounds 2 and 4 showed antifungal activity, with 100 μg against Fusarium oxysporum f. sp. lycopersici.
Thalifoline Description
Source: The herbs of Thalictrum aquilegifolium
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.8263 mL 24.1313 mL 48.2625 mL 96.5251 mL 120.6564 mL
5 mM 0.9653 mL 4.8263 mL 9.6525 mL 19.305 mL 24.1313 mL
10 mM 0.4826 mL 2.4131 mL 4.8263 mL 9.6525 mL 12.0656 mL
50 mM 0.0965 mL 0.4826 mL 0.9653 mL 1.9305 mL 2.4131 mL
100 mM 0.0483 mL 0.2413 mL 0.4826 mL 0.9653 mL 1.2066 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Australian Journal of Chemistry.1981;34(1):195 - 207.
Alkaloids of Cryptocarya longifolia: X-Ray Crystal Structure of Thalifoline and Longifolonine.[Reference: WebLink]

METHODS AND RESULTS:
The known alkaloids reticuline (1), coclaurine (3), N-methylcoclaurine (2), laurotetanine (7), N-methyl-laurotetanine (8), laurolitsine (10), isoboldine (9), norisocorydine (6), norargemonine (ll), bisnorargemonine (12), Thalifoline (16) and scoulerine (13) were isolated from the New Caledonian plant Cryptocarya longifolia together with two new bases, longifolidine (4) and longifolonine (14).
CONCLUSIONS:
Spectroscopic methods were used for identification and structural investigation, and X-ray crystallographic analysis to determine the structures of Thalifoline and longifolonine.
Chemistry of Natural Compounds, 2017,53( 3) : 504–7.
Isoquinoline Alkaloids from Michelia fuscata[Reference: WebLink]

METHODS AND RESULTS:
Two new isoquinoline alkaloids, fuscatine A (1) and fuscatine B (2), along with 21 compounds including eight isoquinoline alkaloids, norThalifoline (3), Thalifoline (4), corydaldine (5), N-methylcorydaldine (6), (6,7-dimethoxyisoquinolinyl)-(4′-methoxyphenyl)-methanone (7),(6,7-dimethoxyisoquinolinyl)-(4′-hydroxyphenyl)-methanone (8), liriodenine (9), and corydine (10); two steroids, β-sitosterone and stigmasterone; six benzenoids, p-hydroxybenzaldehyde, p-hydroxybenzoic acid, 3,4-dimethoxybenzoic acid, methylparaben, syringic acid, and coniferyl aldehyde; one quinone 2,6-dimethoxy-p-benzoquinone, and one sesquiterpene, caryophyllene oxide, are isolated from the stems of Michelia fuscata (Magnoliaceae).
CONCLUSIONS:
These compounds were characterized and identified by physical and spectral analysis.
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