Vellosimine | CAS:6874-98-2 | Manufacturer ChemFaces

Vellosimine

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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Vellosimine Description

Source:	The herbs of Rauvolfia verticillata
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Org Lett. 2000 Jul 13;2(14):2057-9.

General approach for the synthesis of sarpagine/ajmaline indole alkaloids. Stereospecific total synthesis of the sarpagine alkaloid (+)-vellosimine.[Pubmed: 10891229]

METHODS AND RESULTS:
(+)-Vellosimine has been synthesized enantiospecifically in 27% overall yield from commercially available D-(+)-tryptophan methyl ester via the asymmetric Pictet-Spengler reaction and a stereocontrolled intramolecular palladium-coupling reaction as key steps.

Angew Chem Int Ed Engl. 2015 Jan 2;54(1):315-7.

Enantioselective, protecting-group-free total synthesis of sarpagine alkaloids--a generalized approach.[Pubmed: 25346454]

METHODS AND RESULTS:
A generalized synthetic access to sarpagine alkaloids through a joint synthetic sequence has been accomplished. Its applicability is showcased by the enantioselective total syntheses of Vellosimine (1), N-methylVellosimine (3), and 10-methoxyVellosimine (8).

Product Name	Vellosimine
Price:
CAS No.:	6874-98-2
Catalog No.:	CFN97884
Molecular Formula:	C₁₉H₂₀N₂O
Molecular Weight:	292.4 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The herbs of Rauvolfia verticillata
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Alkaloids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.42 mL	17.0999 mL	34.1997 mL	68.3995 mL	85.4993 mL
5 mM	0.684 mL	3.42 mL	6.8399 mL	13.6799 mL	17.0999 mL
10 mM	0.342 mL	1.71 mL	3.42 mL	6.8399 mL	8.5499 mL
50 mM	0.0684 mL	0.342 mL	0.684 mL	1.368 mL	1.71 mL
100 mM	0.0342 mL	0.171 mL	0.342 mL	0.684 mL	0.855 mL

CFN97884	Vellosimine	6874-98-2	292.4	C₁₉H₂₀N₂O
CFN92612	(+)-Affinisine	2912-11-0	308.4	C₂₀H₂₄N₂O
CFN96211	Macusine B	6792-07-0	309.4	C₂₀H₂₅N₂O
CFN96170	Spegatrine	47326-53-4	325.4	C₂₀H₂₅N₂O₂
CFN96097	10-Hydroxy-16-epiaffinine	82513-70-0	340.4	C₂₀H₂₄N₂O₃
CFN96181	Pelirine	30435-26-8	354.5	C₂₁H₂₆N₂O₃
CFN96148	Taberpsychine	19452-84-7	308.4	C₂₀H₂₄N₂O
CFN97989	N-Methoxyanhydrovobasinediol	125180-42-9	338.5	C₂₁H₂₆N₂O₂
CFN96030	16-Epivoacarpine	114027-38-2	368.4	C₂₁H₂₄N₂O₄
CFN96018	Gelsempervine A	865187-17-3	382.5	C₂₂H₂₆N₂O₄