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Natural Products
Catalog No. Information
CFN90046 D-Mannitol

D-Mannitol, a specific hydroxyl free radical scavenger, can reduce the developmental toxicity of hydroxyurea in rabbits; it has thermal properties and could be as a Phase Change Material (PCM) for latent heat storage system; it is a potential diagnostic marker for aspergillosis. D-mannitol has neuroprotectant effect in reducing the sensory neurological disturbances seen in ciguatera poisoning, it does not act purely as an osmotic agent to reduce swelling of nerves, but involves a more complex action dependent on the Na(v) channel subtype, possibly to alter or reduce toxin association.
CFN91717 D-Mannose

D-Mannose has anti-inflammatory and antitumor activity. D-Mannose plays an important role in immune regulation. IC50 & Target: Human Endogenous Metabolite
CFN98125 D-Menthol

Menthol is a common compound in pharmaceutical and commercial products and a popular additive to cigarettes, it attenuates α7 mediated Ca 2+ transients in the cell body and neurite, suggests that menthol inhibits α7-nACh receptors in a noncompetitive manner. Menthol has cooling sensation in the skin, by chemically triggering the cold-sensitive TRPM8 receptors. Menthol has analgesic property, it acts as a noncompetitive antagonist of the 5-HT3 receptor.
CFN98517 Docetaxel

Docetaxel is an antineoplastic drug by inhibiting microtubule depolymerization, and attenuating of the effects of bcl-2 and bcl-xL gene expression.
CFN98349 Docosyl caffeate

Docosyl caffeate shows moderate antioxidant activity in DPPH and ABTS scavenging assays, it also has significant anti-inflammation activity. Docosyl caffeate exhibits potent elastase inhibitory activity, with the IC50 value of 1.4 microg/mL.
CFN96016 Dodoviscin A

Dodoviscin A may be a new promising pigmentation-altering agent for cosmetic and therapeutic applications, it can inhibit melanin biosynthesis induced by 3-isobutyl-1-methylxanthine and PD98059.Dodoviscin A can promote adipocyte differentiation as characterized by increased triglyceride levels in 3T3L1 cells, it can enhance the accumulation of lipid droplets and induce upregulation of the expression of the adipocyte-specific genes aP2 and GLUT4.
CFN90036 Dopamine hydrochloride

Dopamine hydrochloride is a catecholamine neurotransmitter present in a wide variety of animals,And a dopamine D1-5 receptors agonist.
CFN96193 Dorsmanin A

Dorsmanin A is a natural product from Psoralea corylifolia.
CFN60027 Doxorubicin Hydrochloride

Doxorubicin (Adriamycin, NSC 123127, DOX) HCl is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage, mitophagy and apoptosis in tumor cells. Doxorubicin reduces basal phosphorylation of AMPK. Doxorubicin is used in the concomitant treatment of HIV-infected patients but is found to be at high risk of HBV reactivation.
CFN90251 Doxycycline

Doxycycline, an inhibitor of matrix metalloproteinases, has beneficial effects on sulfur mustard-induced ocular pathologies depend on the injury stage. Doxycycline inhibits B cell, MC and histamine function and attenuates experimental allergic conjunctivitis and systemic anaphylaxis by possible modulating the PI3K/Akt pathway.Doxycycline treatment of microfilaremic dogs gradually reduces numbers of microfilariae and blocks further transmission of heartworms, also has a slow-kill effect on adult heartworms.