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Natural Products
Catalog No. Information
CFN98753 Isoquercitrin

Isoquercitrin has anti-tumoral, antihypertensive, anti-osteoporosis, anti-allergy, anti-inflammatory, and antiasthmatic activities, it also may be as a potential therapeutic agent against neurodegeneration in Parkinson's disease. Isoquercitrin is an inhibitor of Wnt/β-catenin that acts downstream of the β-catenin nuclear translocation; it is also a potential stimulator of bone mineralization used for prophylaxis of osteoporotic disorders. Isoquercitrin inhibited carbachol and leukotriene D4 -induced contraction in guinea-pig airways, and it induced hypotension in rats is an event dependent on the inhibition of angiotensin II generation by angiotensin converting enzyme (ACE).
CFN98735 Isorhamnetin

Isorhamnetin, a natural flavonol aglycon, is a tyrosinase inhibitor and has anti-adipogenic, cardioprotective, anti-tumor, and antioxidant activities. it inhibits the H(2)O(2)-induced activation of the intrinsic apoptotic pathway via ROS scavenging and ERK inactivation, it inhibits NF-κB signaling. Isorhamnetin prevents angiotensin II (AngII)-induced endothelial dysfunction by inhibiting the overexpression of p47(phox) and the subsequent increases O2-production, resulting in increased nitric oxide bioavailability.
CFN91130 Isorhamnetin 3,7-O-diglucoside

Isorhamnetin 3,7-O-diglucoside may have antioxidant activity.
CFN90739 Isorhamnetin 3-glucoside-7-rhamnoside

An anti-oxidative composition containing isorhamnetin-3-glucoside-7-rhamnoside (IGR)isolated from Hippophae rhamnoides L. is provided to ensure antioxidative, antibacterial, and anti-cancer effect; a cosmetic composition for preventing or treating aging contains IGR compound as an active ingredient; a health food composition for antioxiaiton contains IGR as an active ingredient; a pharmaceutical composition for antibacterial and anticancer contains IGR as an active ingredient.
CFN90568 Isorhamnetin 3-glucuronide

Isorhamnetin 3 -O -glucuronide exerts anti-inflammatory activity by increasing heme oxygenase-1 (HO-1) expression and by suppressing Jun N-terminal kinase (JNK) and p38 signaling pathways in LPS-challenged RAW264.7 macrophage cells. Isorhamnetin 3-glucuronide can inhibit vascular cell adhesion molecule-1 (VCAM-1) cell surface expression at 2 micromol/L, indicates that it can inhibit the expression of key molecules involved in monocyte recruitment during the early stages of atherosclerosis at physiological concentrations. It (1 mg/kg i.v.) can progressively reduce mean blood pressure (MBP), measured in conscious spontaneously hypertensive rats (SHR).
CFN91845 Isorhamnetin 3-O-beta-D-glucose-7-O-beta-D-gentiobioside

Reference standards.
CFN93036 Isorhamnetin 3-O-galactoside

Isorhamnetin 3-O-galactoside shows antioxidant, anti-inflammatory, neuroprotective,and barrier protective activities, it could be used as a candidate therapeutic for treatment of severe vascular inflammatory diseases.It has potential anticoagulant activity, it possesses antithrombotic and profibrinolytic activity and offers bases for development of a novel anticoagulant. Isorhamnetin 3-O-galactoside is also a 5-lipoxygenase inhibitor, it may have therapeutic potential in skin inflammatory disorders in traditional medicine.
CFN93057 Isorhamnetin 3-robinobioside

Isorhamnetin 3-O-robinobioside has a great antioxidant and antigenotoxic potential on human chronic myelogenous leukemia cell line K562.
CFN90735 Isorhamnetin 3-sophoroside-7-rhamnoside

Isorhamnetin 3-sophoroside-7-rhamnoside is a natural product from Elaeagnus multiflora Thunb.
CFN91087 Isorhamnetin 7-O-alpha-L-rhamnoside

Reference standards.