Hot Products
| Catalog No. | Information |
| CFN91071 | Isosilybin B Isosilybin B causes androgen receptor degradation in human prostate carcinoma cells via PI3K-Akt-Mdm2-mediated pathway, it has anti-prostate cancer (PCA) activity that is mediated via cell cycle arrest and apoptosis induction. Isosilybin B showed inhibitory effect on CYP2C8 activity. It inhibited both monophenolase (IC50 = 1.7-7.6 μM) and diphenolase (IC50 = 12.1-44.9 μM) of tyrosinase. |
| CFN90806 | Isosinensetin Isosinensetin shows antioxidant and HIV-1 protease inhibiting activities. |
| CFN95350 | Isospinosin |
| CFN90544 | Isosteviol Isosteviol possesses various biological activities including anti-hyperglycemic, anti-hypertensive, anti-tumor, anti-inflammatory, neuroprotective, antibacterial, antifungal,and antioxidant effects.Isosteviol plays a protective role in a variety of stress-induced cardiac diseases, it can prevent the prolongation of action potential in hypertrophied cardiomyoctyes by regulating transient outward potassium and L-type calcium channels. |
| CFN98398 | Isotachioside Isotachioside has15-lipoxygenase (15-LO) inhibitory activities. |
| CFN90356 | Isotanshinone I Isotanshinone I ,neotanshinone A and cryptotanshinone have different effects on inhibiting proteic activity of P38 and NF-κB signaling pathway,and this effect may be one of main mechanisms of inhibitive inflammation reaction by salvia miltiorrhiza bunge in liver. |
| CFN92020 | Isotanshinone II Reference standards. |
| CFN90357 | Isotanshinone IIA Isotanshinone IIA non-competitively inhibits protein tyrosine phosphatase 1B (PTP1B) activity with 50% inhibitory concentration values of 11.4±0.6 μM. PTP1B acts as a negative regulator of insulin signaling, and selective inhibition of PTP1B has served as a potential drug target for the treatment of type 2 diabetes. |
| CFN98722 | Isotetrandrine Isotetrandrine is a small molecule inhibitor, on various aspects of LPS-induced inflammation in vitro and in vivo. It dose-dependently suppresses the severity of LPS-induced ALI by inactivation of MAPK and NF-κB, which may involve the inhibition of tissue oxidative injury and pulmonary inflammatory process. |
| CFN92436 | Isothymonin Isothymonin has antioxidant activity.It displays cyclooxygenase-1 inhibitory activity. |
