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Natural Products
Catalog No. Information
CFN80321 Methylophiopogonone B

Methylophiopogonone B is a natural product from Ophiopogon japonicus.
CFN92450 Methylsynephrine Hydrochloride

Reference standards.
CFN92148 Methyltanshinonate

Methyltanshinonate shows antiplasmodial and antitrypanosomal activities. It may have antioxidative activity.
CFN90160 Methysticin

Methysticin is a potent NF-kappaB inhibitor in kava with minimum toxicity, it possesses hepatotoxic, anticonvulsant and neuroprotective properties, it contributes to CYP1A1 induction.
CFN90426 Mevastatin

Mevastatin inhibits HMGCR (HMG-CoA reductase) which in turn inhibits isoprenoid biosynthesis and therefore blocks protein isoprenylation and reduces plasma cholesterol levels in humans. Mevastatin inhibits the differentiation of TAO derived orbital preadipocytes by blocking PPAR-gamma mRNA expression. Mevastatin induces cell growth inhibition and apoptosis in SACC cells, it triggers the phosphorylation of the EGFR and inhibits the c-Jun N-terminal kinase pathway.
CFN91035 Micheliolide

Micheliolide has antineoplastic, anti-inflammatory and immunomodulatory effects, it inhibits various inflammatory response and may serve as a neuroprotective agent in neuroinflammation-related neurodegenerative disorders. Micheliolide has potential as a candidate drug for the treatment of diabetic nephropathy, it can effectively attenuate the high glucose-stimulated activation of NF-κB, the degradation of IκBα, and the expression of MCP-1, TGF-β1 and FN in rat mesangial cells (MCs). Micheliolide also ameliorates liver steatosis by upregulating PPAR-γ expression, thereby inhibiting NF-κB-mediated inflammation and activating AMPK/mTOR-dependent autophagy.
CFN97124 Micranoic acid A

Reference standards.
CFN70417 Miliacin

Miliacin weakens the severity of salmonellosis infection course.It can produce a protective effect on splenocytes by decreasing the degree of DNA fragmentation due to blockade of the cascade cell death distally to the intramembrane phosphatidylserine translocation.
CFN90409 Militarine

Militarine has plant inhibitory effect against the growth of Italian ryegrass, timothy, and B. striata.
CFN98531 Miltirone

Miltirone is a CYPs inhibition, it has been characterized as a low-affinity ligand for central benzodiazepine receptors, it might ameliorate the symptoms associated with discontinuation of long-term administration of ethanol or of other positive modulators of the GABA A receptor. Miltirone possesses significant anticancer, antibacterial, antioxidant, and anti-inflammatory activities, the hepatocyte metabolism is the major route of clearance for miltirone. Miltirone is collateral sensitive in multidrug-resistant P-gp-overexpressing cells, induces G2/M arrest, and triggeres apoptosis via ROS-generated breakdown of MMP and DNA damage. Miltirone has antiprotozoal activity against T. brucei rhodesiense STIB 900.