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Natural Products
Catalog No. Information
CFN98836 Maclurin

Maclurin can effectively protect against mesenchymal stem cells (MSCs) oxidative damage induced by hydroxyl radical (OH) at 62.1-310.5 uM, the protective and antioxidant effects of maclurin can be primarily attributed to ortho-dihydroxyl groups, and ultimately to the relative stability of the ortho-benzoquinone form.Maclurin has anti-metastatic effect, the mechanism is by anti-oxidative activity and inhibition of Src/FAK-ERK-β-catenin signaling pathway.
CFN90672 Macranthoidin A

Macranthoidin A, found in the herbs of Lonicera japonica Thunb., has anti-inflammation activity.
CFN99148 Macranthoidin B

Macranthoidin B is a major bioactive saponin in rat plasma after oral administration of extraction of saponins from Flos Lonicerae.
CFN99413 Macrocarpal A

Macrocarpal A is the key component that stimulates the synthesis of ceramide in the stratum corneum. Macrocarpal A has cytotoxic, and antibacterial activities.
CFN99472 Macrocarpal B

The intestinal absorption of M-A, Macrocarpal B, and Cy-C was passive diffusion as the dominating process and Cy-C was partly ATP-dependent.
CFN99469 Macrocarpal C

Macrocarpal C, isolated from the fresh leaves of Eucalyptus globulus Labill. (Lan An) and identified as its major antifungal component by bioassay-guided purification, the antifungal action of macrocarpal C was associated with increases of membrane permeability, intracellular ROS and DNA fragmentation.
CFN99841 Macrocarpal H

Macrocarpal H has anti-glucosyltransferase, and anti-bacterial activities.
CFN99842 Macrocarpal I

Macrocarpal I has anti-glucosyltransferase, and anti-bacterial activities.
CFN99914 Madecassic acid

Madecassic acid has anti-diabetic, anti- tumor, wound-healing, and anti-inflammatory properties, it can improve glycemic control and hemostatic imbalance, lower lipid accumulation, and attenuate oxidative and inflammatory stress in diabetic mice. It can protect against hypoxia-induced oxidative stress in retinal microvascular endothelial cells via ROS-mediated endoplasmic reticulum stress. It inhibited the esspession of NOS, COX-2, TNF-alpha, IL-1beta, IL-6, and the downregulation of NF-kappaB activation.
CFN99913 Madecassoside

Madecassoside is a mechanism-based inhibitor of CYP2C19 and CYP3A4, which has antioxidant, anti-inflammatory, anti-apoptosis, wound-healing, and neuroprotective activities, It may have cardioprotective effects in LPS-mediated through inhibition of ERK, p38, and NF-κB activity, it inhibited the pro-inflammatory mediators, including COX-2 expression, PGE2 production, TNF-αand IL-6 levels and the up-regulation anti-inflammatory molecule IL-10.