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Natural Products
Catalog No. Information
CFN99565 Picroside I

Picroside I is a hepatoprotective agent which is reported to be antimicrobial and used against hepatitis B. It has antioxidant, and anti-inflammatory activities, it may be the valuable anti-invasive drug candidates for cancer therapy by suppressing Collagenases and Gelatinases. Picroside I can enhance basic fibroblast growth factor(bFGF)-, staurosporine- or dbc-mitogen-activated protein (MAP)-induced neurite outgrowth from PC12D cells.
CFN99566 Picroside II

Picroside II has antioxidant, anti-inflammatory, immune regulatory, anti-virus and other pharmacological activities. It has potent anti-apoptotic activity against renal I/R injury by suppressing the TLR4/NF-κB signaling pathway, it can protect the ischemic kidney against renal fibrosis and improve the neurological function of rats upon cerebral ischemia reperfusion injury. Picroside II enhances nerve growth factor (NGF)-induced neurite outgrowth from PC12D cells by amplifying a down-stream step of MAP kinase in the NGF receptor-mediated intracellular MAP kinase-dependent signaling pathway.
CFN99567 Picroside III

Picrosides exhibit significant learning and memory deficits, just as Alzheimer's disease(AD) in human.
CFN90868 Picroside IV

Kutkoside is a mixture of iridoid glycosides namely, picroside II, Picroside IV and 6-ferulloylcatalpol, it may have antinociceptive and anti-inflammatory effects.
CFN70291 Picrotoxinin

Picrotoxinin and bicuculline may antagonize GABA responses by stabilizing the closed form of the activated channel, whereas penicillin-G may block the channel in the open state.
Picrotoxin is an inducer of phenobarbital-inducible liver enzymes.
CFN95226 Pieceid-2''-O-gallate

Pieceid-2''-O-gallate has antioxidant activity.
CFN96503 Pilloin

Pilloin exerts a cytotoxic action targeted at the transformed lymphoblasts.
CFN70491 Pilocarpine

Pilocarpine has been used to treat glaucoma, ocular hypertension and xerostomia. Pilocarpine can induce seizures. It antagonizes prostaglandin F2 alpha-induced ocular hypotension in monkeys. the ability of oral pilocarpine to normalise and reverse the salivary biochemical and immunological alterations induced by cGVHD parallels its known stimulatory effect on salivary flow rates. The combination of pilocarpine and sorbitol has effective antimicrobial activity.
CFN93245 Pilocarpine Hydrochloride

Pilocarpine hydrochloride appears to be effective for dry mouth associated with Sjögren's syndrome. It has acaricidal activity.
CFN99382 Pimaric acid

Pimaric acid has potent anti-atherosclerotic activity with inhibitory action on matrix metalloproteinase-9 production and cell migration in TNF-α-induced human aortic smooth muscle cells. 4-epi-Pimaric acid shows antibacterial, anti-biofilm and anti-inflammatory potency , can be exploited for therapeutic application in oral microbial infections.