Hot Products
Catalog No. | Information |
CFN99868 | Odoroside H Odoroside H has anticancer activities, the cytotoxic effects are induced by the inhibition of the plasma membrane bound Na(+)/K(+)-ATPase. |
CFN91651 | Oenothein B Oenothein B is a dimeric macrocyclic ellagitannin and has widely pharmacological activities, including antioxidant, anti-inflammatory, antifungal, anti-HCV, and antitumor properties. Oenothein B is a potent and specific inhibitor of poly(ADP-ribose) glycohydrolase. |
CFN90692 | Officinalisinin I Officinalisinin Ⅰcan effectively reduce the blood glucose and protect nerve injuryin diabetic mice. |
CFN92687 | Officinaruminane B Standard reference |
CFN97704 | Ohchinin Ohchinin exhibits potent inhibitory activities with 26 - 66% reduction of melanin content at 100 μm concentration with almost no or low toxicity to the B16 melanoma cells (70 - 99% cell viability at 100 μm). |
CFN90849 | Okanin 1. Okanin shows significant activities on both linoleic acid peroxidation inhibition and DPPH radical scavenging effect. 2. Okanin shows significant protective effects against tacrine-induced cytotoxicity in human liver-derived Hep G2 cells with the EC50 value of 29.8±1.1 uM. 3. Okanin can inhibit nitric oxide production and inducible nitric oxide synthase expression via nuclear factor-erythroid 2-related factor 2-dependent heme oxygenase-1 expression in lipopolysaccharide-activated macrophages. 4. Okanin attenuates LPS-induced microglial activation through inhibition of the TLR4/NF-κB signaling pathways, suggests that okanin may have potential as a nutritional preventive strategy for neurodegenerative disorders. |
CFN60045 | Olaparib (AZD2281) Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1/2 with IC50 of 5 nM/1 nM in cell-free assays, 300-times less effective against tankyrase-1. Olaparib induces significant autophagy that is associated with mitophagy in cells with BRCA mutations. |
CFN90395 | Olaquindox Olaquindox, as one of the antimicrobial growth accelerants, is usually used in livestock production to improve feed efficiency. Olaquindox induces apoptosis of HepG2 cells through a caspase-9 dependent mitochondrial pathway, might be suppressed through p38 MAPK and ROS-JNK pathways; it induces autophagy in HepG2 cells is upregulated by Beclin 1 but downregulated by ROS-dependent JNK.Olaquindox has genotoxic activity. |
CFN70276 | Oleacein Oleacein has antioxidant, anti-metastatic, anticancer, and anti-inflammatory activities, it inhibits STAT3, activates the apoptotic machinery. Oleacein can be used as an adjuvant to improve insulin sensitivity in humans, and it could play a potential role in the prevention of inflammatory disease related to atherosclerosis. |
CFN98871 | Olean-12-ene-3,11-diol Reference standards. |