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Natural Products
Catalog No. Information
CFN70384 Nordihydroguaiaretic acid

Nordihydroguaiaretic acid(NDGA), an inhibitor of lipoxygenase, also inhibits cytochrome P-450-mediated monooxygenase activity in rat epidermal and hepatic microsomes. NDGA has anti-inflammatory, antimutagen and/or anticarcinogen activities. NDGA protects hippocampal neurons against amyloid β-peptide toxicity, and attenuates free radical and calcium accumulation, it can interupt a neurodegenerative pathway relevant to the pathophysiology of Alzheimer's disease. NDGA protects against high-fat diet-induced fatty liver by activating AMP-activated protein kinase in obese mice. NDGA-crosslinking of decellularized valvular matrix is a promising approach for preparation of heart valve tissue engineering scaffolds.
CFN90047 Norepinephrine

Norepinephrine is a peripheral vasoconstrictor by acting on alpha-adrenergic receptors, it can up-regulate the expression of vascular endothelial growth factor, matrix metalloproteinase (MMP)-2, and MMP-9 in nasopharyngeal carcinoma tumor cells. Norepinephrine can stimulates apoptosis in adult rat ventricular myocytes by activation of the β-adrenergic pathway. Noradrenergic system may play a significant role in modulating the development of ischemic neuronal damage.
CFN99027 Noreugenin

Reference standards.
CFN98528 Noricaritin

Reference standards.
CFN99528 Norisoboldine

Norisoboldine produces anti-inflammatory and anti-rheumatoid arthritis effects, it produces the analgesic effect in inflammatory pain by a mechanism related to the adenosine system. Norisoboldine alleviated joint destruction in AIA rats by reducing RANKL, IL-6, PGE2, and MMP-13 expression via the p38/ERK/AKT/AP-1 pathway, it decreased forskolin-evoked cyclic adenosine monophosphate levels in mouse spinal cord neuronal cultures through the adenosine A1 receptor.
CFN92409 Norjuziphine

Norjuziphine has antiplatelet aggregation activity.
CFN98041 Norlichexanthone

Norlichexanthone has the potential to treat and/or prevent lifestyle-related diseases, including metabolic syndrome, type 2 diabetes, atherosclerosis and cardiovascular diseases.Norlichexanthone has antibacterial and antimalarial activities, it shows strong activity against Bacillus subtilis with IC50 in the range of 1-5uM, it also significantly inhibits the growth of methicillin-resistant Staphylococcus aureus with IC50 of 20.95±1.56uM.
CFN90504 Noroxyhydrastinine

Noroxyhydrastinine exhibits potent melanogenesis-inhibitory activities, it inhibits melanogenesis, at least in part, by inhibiting the expression of protein levels of tyrosinase, TRP-1, and TRP-2 in α-MSH-stimulated B16 melanoma cells.
CFN92811 Norsanguinarine

Norsanguinarine has antifungal activity, it exhibits 100 % inhibition of A. brassicicola and C. maculans at 1000 ppm whereas. It shows significant cytotoxic activities (ED (50) values < 4 microg/ml) against P-388, KB16, A549, and HT-29 cell lines.
CFN96076 Norscopolamine

Reference standards.