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Natural Products
Catalog No. Information
CFN98156 Ophiopogonin D

Ophiopogonin D plays a protective role as an effective antioxidant in H2O2-induced endothelial injury, it can attenuate doxorubicin-induced autophagic cell death by relieving mitochondrial damage in vitro and in vivo, it can be therefore developed as a novel drug for the therapy of cardiovascular disorders. Ophiopogonin D and spicatoside A can increase mucin production and secretion, by directly acting on airway epithelial cells, they could be as expectorants in diverse inflammatory pulmonary diseases. Ophiopogonin D inhibits MCF-7 cell growth via the induction of cell cycle arrest at the G2/M phase.
CFN90503 Ophiopogonin D'

Ophiopogonin D' can activate SIRT1, it also noncompetitively inhibits UGT1A6 and UGT1A10.
CFN99164 Oridonin

Oridonin has anticancer activity, might be useful as adjunctive therapy for individuals with lymphoid malignancies, including the lethal disease adult T-cell leukemia.It inhibits tumor growth in glioma by inducing cell cycle arrest and apoptosis, inhibits BxPC-3 cell growth through cell apoptosis.
CFN95136 Orientalide

Reference standards.
CFN98136 Orientin

Orientin has various activities including anti-oxidant, anti-aging, anti-viral, anti-bacterial, anti-inflammation, vasodilatation and cardioprotective, antiadipogenesis, antinociceptive, radiation protective, neuroprotective, and antidepressant-like effects. Orientin protects H9c2 cardio-mytocytes against I/R-induced apoptosis by modulating the mPTP opening, and this role of orientin may involve the PI3K/Akt signaling pathway; it also can decrease C/EBPα and PPARγ protein expression level in 3T3-L1 cells.
CFN89504 Orobanchyl acetate

Orobanchyl acetate is a germination stimulant for root parasitic plants.
CFN98737 Orobol

Orobol is an inhibitor of tyrosine-specific protein kinase and phosphatidylinositol turnover, it has sensitization effect, it can produce produced cisplatin (DDP) sensitivity in human ovarian carcinoma cells by inducing apoptosis through the MT-dependent signaling pathway. Orobol and platelet derived growth factor (PDGF) regulate paclitaxel (PX) sensitivity by reciprocally altering the proportion of tubulin isotype expression and PX-induced apoptotic signaling. Orobol exhibits antiviral effects against some animal viruses, addition of the compound after virus entry inhibits the appearance of late viral protein synthesis in Vesicular Stomatitis Virus, influenza, or vaccinia virus-infected cells, but has no effect on poliovirus protein synthesis.
CFN95001 Oroselol

Oroselol, jatamansinol, nardostachysin, jatamansinone and nardosinone are Nardostachys jatamansi rhizome extract marker compounds.
CFN99712 Oroxin A

Oroxin A is a xanthine oxidase (XO) inhibitor, it exerts its antibreast cancer effects by inducing ER stress-mediated senescence, activating the key stress signaling pathway, and increasing key ER stress genes and expression levels.
CFN99713 Oroxin B

Oroxin B can selectively induce tumor-suppressive ER stress and concurrently inhibit tumor-adaptive ER stress in B-lymphoma cells for effective anti-lymphoma therapy.