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Natural Products
Catalog No. Information
CFN90020 Roflumilast

Roflumilast is a phosphodiesterase 4 inhibitor that may improve lung function and reduce the frequency of exacerbations in patients with COPD. Roflumilast has anti-inflammatory and immunomodulatory potential,it will be useful in the treatment of chronic inflammatory disorders such as asthma and chronic obstructive pulmonary disease. Suppression of hematological and immunological markers of inflammation and enhanced apoptosis in animals treated with Roflumilast points to the possibility of a beneficial effect of Roflumilast in allergic inflammation.
CFN89097 Rosamultin

Rosamultin has antioxidant, antiinflammatory/antinociceptive properties, it may protect against bromobenzene-induced hepatotoxicity through, at least in part, enhanced activity of epoxide hydrolase. Rosamultin has anti-human immunodeficiency virus (HIV) activity, it inhibited HIV-1 protease by 53% at a concentration of 100 microM.
CFN99178 Rosarin

Rosarin is a natural product from Rhodiola rosea L.
CFN99179 Rosavin

Rosavin possesses anti-fatigue, antidepressant and anxiolytic activities, it decreased neovascular reaction on cutaneous angiogenesis induced in mice after grafting of syngeneic tumor cells.
CFN98916 Roseoside

Roseoside possesses strong antioxidant properties, inhibiting lipid oxidation by 86.4, at 50 microg/mL. Roseoside has insulinotropic activity, enhances insulin release from the β-cell line INS-1.Roseoside can significantly delay carcinogenesis induced by peroxynitrite (initiator) and TPA (promoter). (6S,9R)-Roseoside also can inhibit the histamine release from rat peritoneal exudate cells induced by antigen-antibody reaction.
CFN60270 Rosiglitazone

CFN99180 Rosin

Rosin may have therapeutic potential for the treatment of inflammation and neurodegenerative disease.Rosin may cause allergic contact dermatitis in eyeshadow and mascara.
CFN99181 Rosiridin

Rosiridin has cardioprotective activity.
CFN93024 Rosmanol

Rosmanol has antioxidant activity, it can activate the antioxidant response element, it also has biphasic modulation of GABAA receptors, demonstrates CNS activity in mouse models of antinociception, antidepressant and anxiolysis. Rosmanol exhibits significant cytotoxicity towards the neuroblastoma cells, it potently induces apoptosis through both the mitochondrial apoptotic pathway and death receptor pathway in human colon adenocarcinoma COLO 205 cells.Rosmanol has anti-inflammatory activity, it potently inhibits lipopolysaccharide-induced iNOS and COX-2 expression through downregulating MAPK, NF-kappaB, STAT3 and C/EBP signaling pathways.
CFN99103 Rosmarinic acid

Rosmarinic acid has antiviral, antibacterial, antiinflammatory, neuroprotective, anticancer, anti-lipid peroxidative, apoptotic,and antioxidant activities. It is used for food preservation, and to treat peptic ulcers, arthritis, cataract, cancer, rheumatoid arthritis, bronchial asthma, and several human neurodegenerative diseases caused by oxidative stress. Rosmarinic acid has the ability to block complement fixation, inhibit lipoxygenase and cyclooxygenase activity and inhibit the expression of CCL11 and CCR3 by suppressing the IKK-β activity in NF-κB activation signaling. It inhibits MAO-A, MAO-B and COMT enzymes with IC50s of 50.1, 184.6 and 26.7 μM, respectively.