Screening Libraries
| Cat. | Size | Price | Stock | |
| L20216 | 1mg/well * 26 Compounds | Inquiry | In stock | Contact Us |
| L20216 | 100uL/well (10mM solution) * 26 Compounds | Inquiry | In stock |
| manager@chemfaces.com | |
| Tel | (0086)-27-8423-7683 |
| Shelf Life | (0086)-27-84254680 |
| Manufacturer | Wuhan ChemFaces Biochemical Co., Ltd. |
| Container | 96 Well Format Sample |
| Storage | Protected from air and light, refrigerate or freeze(2-8 °) |
| Shelf Life | 24 months (2-8 °) |
| Intended Use | For research use only. Not for human use. Not sell to patients |
| 1. The products in the ChemFaces screening libraries are all from plants. |
| 2. The biological activities or pharmacological activities of all the ChemFaces products are derived from the databases of all over the world the latest literatures, you can according to the product manuals on our website to access the relevant literatures, hope that our informations can give some inspirations and help to your research. |
| 3.The collections of unique natural products, which include antioxidants, anti-inflammatory, antibacterial, anticancer, and ect. Can be used for high throughput screening (HTS) and high content screening (HCS), is to help you carry out new drug screening, the emergence of new indications and other professional tools. |
| 4.Structurally diverse, medicinally active, and cell permeable, NMR and HPLC validated to ensure high purity. |
| 5. ChemFaces offers customized bioactive screening libraries , whereby you choose the specific compounds you want in the library, the quantities, plate map, concentration, and format (dry/solid or DMSO solution). |
| Catalog No. | Information |
| CFN99166 | Tetrandrine Tetrandrine is a calcium channel blocker, which shows antitumor, antifibrotic, anti-oxidant, anti-inflammatory and immunosuppressive activity. It suppressed Wnt/β-catenin signaling transduction, the migration of DU145 and PC-3 cells, EOMA cell growth through the ROS/Akt pathway and inhibited inward rectifying potassium current in cultured bovine aortic endothelial cells. |
| CFN99512 | L-Nicotine Nicotine is a potent inhibitor of cardiac A-type K+ channels, with blockade probably due to block of closed and open channels, this action may contribute to the ability of nicotine to affect cardiac electrophysiology and induce arrhythmias.Nicotine is able to activate mitogenic signalling pathways, which promote cell growth or survival as well as increase chemoresistance of cancer cells, nicotine activates its downstream signalling to interfere with the ubiquitination process and prevent Bcl-2 from being degraded in lung cancer cells, resulting in the increase of chemoresistance. |
| CFN99707 | Levistilide A Traditional formula compatibility of Danggui-Shaoyao-San could significantly enhance levistilide A bioavailability compared with levistilide A alone and Rhizoma Chuanxiong. |
| CFN99647 | 5,5'-Dimethoxylariciresinol 4-O-glucoside 5,5'-Dimethoxylariciresinol-4'-O-beta-D-glucoside is shown to effectively enhance chemosensitivity of resistant cells, which makes it may be a suitable candidate for potential multidrug resistance (MDR)-reversing agents. |
| CFN98230 | Ecdysterone 2,3:20,22-diacetonide Due to the multi-drug resistance reversal activity of the less polar ecdysteroids, several new products( including 20-hydroxyecdysone,20-hydroxyecdysone 2,3;20,22-diacetonide) are promising for being tested against various cancer cell lines. |
| CFN98115 | Lathyrol Lathyrol diterpenes is a modulator of P-glycoprotein dependent multidrug resistance, and is used for cancer treatment. |
| CFN98559 | Epoxylathyrol Epoxylathyrol derivatives have modulation of ABCB1-mediated multidrug resistance in human colon adenocarcinoma and mouse T-Lymphoma cells. |
| CFN98570 | Cepharanthine Cepharanthine has anti-plasmodial, anti-tumor , anti-inflammatory, antiallergic, antioxidant, and immunomodulatory activities in vivo, and it is a highly potent inhibitor of HIV-1 replication in a chronically infected monocytic cell line. Cepharanthine inhibits the HIV-1 entry process by reducing plasma membrane fluidity, and the plasma membrane is therefore an identical target to prevent viral infection. |
| CFN90042 | Estrone Estrone,a steroid known to play an important role as precursor of 17 beta-estradiol,especially in postmenopausal women, it inhibits the BCRP-mediated drug efflux and overcome drug resistance.The widely distributed estrone esters in food and their relatively high concentrations may result in high free hormone intakes in humans, the continued and massive intake of estrone may enhance tissue deposition and lead to obesity. |
| CFN98759 | Sarpagine Sarpagine is effective in reversing multidrug-resistance (MDR) in vincristine-resistant KB cells. |
