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Screening Libraries
DNA damaging agents Compound Library
A unique collection of 17 DNA damaging agents Compound Library for high throughput screening (HTS), high content screening (HCS) and New drug research
Cat. Size Price Stock
L202181mg/well * 17 CompoundsInquiry In stock
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L20218100uL/well (10mM solution) * 17 CompoundsInquiry In stock
*You can select compounds, quantities, format (dry/solid or DMSO) and plate map to meet your specific requirement.
Contact Us
E-mail manager@chemfaces.com
Tel (0086)-27-8423-7683
Shelf Life (0086)-27-84254680
ManufacturerWuhan ChemFaces Biochemical Co., Ltd.
Package & Storage
Container 96 Well Format Sample
Storage Protected from air and light, refrigerate or freeze(2-8 °)
Shelf Life 24 months (2-8 °)
Intended UseFor research use only. Not for human use. Not sell to patients
Description & Advantages
1. The products in the ChemFaces screening libraries are all from plants.
2. The biological activities or pharmacological activities of all the ChemFaces products are derived from the databases of all over the world the latest literatures, you can according to the product manuals on our website to access the relevant literatures, hope that our informations can give some inspirations and help to your research.
3.The collections of unique natural products, which include antioxidants, anti-inflammatory, antibacterial, anticancer, and ect. Can be used for high throughput screening (HTS) and high content screening (HCS), is to help you carry out new drug screening, the emergence of new indications and other professional tools.
4.Structurally diverse, medicinally active, and cell permeable, NMR and HPLC validated to ensure high purity.
5. ChemFaces offers customized bioactive screening libraries , whereby you choose the specific compounds you want in the library, the quantities, plate map, concentration, and format (dry/solid or DMSO solution).
Natural Products
Catalog No. Information
CFN98238 Vincosamide

Vincosamide can effect relaxation of the supercoiled pBR322 plasmid DNA in the presence of Cu2+.
CFN00284 Indicine N-oxide

Indicine N-oxide, a pyrrolizidine alkaloid present in the plant Heliotropium indicum, shows promising cytotoxic activity in various tumor models that due to its DNA damaging effects and depolymerization of microtubules.
CFN97803 Goniothalamin

Goniothalamin is a natural product that has been demonstrated to induce apoptosis in various cancer cell lines, can induce cytotoxicity and apoptosis on RT4 cells, induce apoptosis on HepG2 liver cancer cells via induction of caspase-3 with less sensitivity on the cell line of Chang cells. Goniothalamin has gastroprotective activity which is inhibited after pre-treatment with NEM (N-ethylmaleimide) and NSAID (non-steroidal anti-inflammatory drugs), highlighting the importance of sulfhydryl compounds and prostaglandins on Goniothalamin activity. Goniothalamin induces oxidative stresses and inhibits the expression of cell wall-associated proteins resulting in growth inhibition of Arabidopsis seedlings.
CFN90482 Demethyl tetrandrine

Demethyl tetrandrine and tetrandrine show inhibition on DNA synthesis, the 50% inhibition doses ( ID50 ) are in L7712 and Sl80 cells are 27.5, 24.5 mg/L and 2.6, 3 .5mg/ L , respectively.
CFN92264 Rabdosin B

Rabdosin B shows cytotoxic activity against three human tumour HepG2, GLC-82 and HL-60 cell lines, it induces significant DNA damage to HepG2 cells in a time- and dose-dependent manner. Rabdosin B at higher concentrations inhibits root growth by affecting both cell length in the mature region and division of meristematic cells.
CFN92315 Epinodosin

Epinodosin induces significant DNA damage to HepG2 cells in a time- and dose-dependent manner.Epinodosin has a biphasic, dose-dependent effect on root growth and a strong inhibitory effect on root hair development in Lactuca sativa L. seedlings.
CFN92434 Effusanin B

Effusanin B shows antibacterial activity. It exhibits DNA-damaging activity in assay which employes DNA-repair deficient (RAD 52Y) and repair proficient (RAD +) yeast strains.
CFN90527 Corydine

Corydine is the adrenolytic and weak cholinergic agent, it shows antimicrobial, and antineoplastic activities. Corydine shows irritant and respiratory stimulant and CNS depressant activities. Injected intravenously in rabbits corydine produced an initial fall in blood pressure followed by a return to normal or above normal.
CFN96041 Cepharadione A

Cepharadione A is a naturally occurring DNA damaging agent.
CFN90617 Hirsutine

Hirsutine has anticancer, cardioprotective, anti‑hypertensive and anti-arrhythmic activities, it also has vasodilatation activity, the mechanism is related to blockade of Ca2+ influx through L-type Ca2+ channels and inhibition of intracellular Ca2+ release may have no relationship with K+ channels. Hirsutine reduces the production of various neurotoxic factors in activated microglial cells and possesses neuroprotective activity in a model of inflammation-induced neurotoxicity.