Screening Libraries
| Cat. | Size | Price | Stock | |
| L20243 | 1mg/well * 6 Compounds | Inquiry | In stock | Contact Us |
| L20243 | 100uL/well (10mM solution) * 6 Compounds | Inquiry | In stock |
| manager@chemfaces.com | |
| Tel | (0086)-27-8423-7683 |
| Shelf Life | (0086)-27-84254680 |
| Manufacturer | Wuhan ChemFaces Biochemical Co., Ltd. |
| Container | 96 Well Format Sample |
| Storage | Protected from air and light, refrigerate or freeze(2-8 °) |
| Shelf Life | 24 months (2-8 °) |
| Intended Use | For research use only. Not for human use. Not sell to patients |
| 1. The products in the ChemFaces screening libraries are all from plants. |
| 2. The biological activities or pharmacological activities of all the ChemFaces products are derived from the databases of all over the world the latest literatures, you can according to the product manuals on our website to access the relevant literatures, hope that our informations can give some inspirations and help to your research. |
| 3.The collections of unique natural products, which include antioxidants, anti-inflammatory, antibacterial, anticancer, and ect. Can be used for high throughput screening (HTS) and high content screening (HCS), is to help you carry out new drug screening, the emergence of new indications and other professional tools. |
| 4.Structurally diverse, medicinally active, and cell permeable, NMR and HPLC validated to ensure high purity. |
| 5. ChemFaces offers customized bioactive screening libraries , whereby you choose the specific compounds you want in the library, the quantities, plate map, concentration, and format (dry/solid or DMSO solution). |
| Catalog No. | Information |
| CFN00058 | Cathinone Cathinone is the main psychoactive constituent of the khat leaf and this alkaloid is a natural amphetamine, cathinone shares the action of amphetamine on CNS as well as its sympathomimetic effects, it induces significant behavioral changes and CNS activation in the hamster by systemic administration.Cathinone has amphetamine-like effects, it can produce increases in blood pressure and in heart rate, and these changes are concomitant with the presence of cathinone in blood plasma, it has in humans euphorigenic and psychostimulant effects. Cathinone has vasoconstrictor activity which is not due to indirect or direct sympathomimetic activity, the coronary vasoconstriction may explain the increased incidence of myocardial infarction in khat chewers, which may arise from coronary vasospasm. |
| CFN00183 | Cocaine Cocaine is a powerfully addictive stimulant drug made from the leaves of the coca plant native to South America, it produces short-term euphoria. Cocaine has a small number of accepted medical uses such as numbing and decreasing bleeding during nasal surgery, it constricts blood vessels, dilates pupils, and increases body temperature, heart rate, and blood pressure. Cocaine sensitizes VTA cells to the excitatory effects of both CRF and orexin-A, thus providing a mechanism by which stress induces Cocaine seeking.Cocaine also can cause headaches and gastrointestinal complications such as abdominal pain and nausea. Because cocaine tends to decrease appetite, chronic users can become malnourished as well. |
| CFN97181 | 8-O-Acetylharpagide 8-O-Acetylharpagide has anti-inflammatory, vasoconstrictor, antibacteria and antiviral activities, it also has a biological activity on isolated smooth muscle preparations from guinea pig. 8-O-Acetylharpagide presents the obvious inhibition on Epstein-Barr virus(EBV) infection, it not only apparently inhibits EBV-VCA,but also alleviates the hyperfunction and effusion of capillary permeability at the early inflammation. |
| CFN90147 | Yohimbine Yohimbine is a potent and relatively nonselective alpha 2-adrenergic receptor (AR) antagonist, with IC50 of 0.6 μM. Yohimbine may augment extinction learning without significant side effects, and as a therapeutic augmentation strategy for exposure therapy in social anxiety disorder. Yohimbine can be used as antagonistic agents against medetomidine-induced diuresis in healthy cats; it inhibits ATP-sensitive K+ channels in mouse pancreatic beta-cells. |
| CFN90164 | Dimethylacrylshikonin Dimethylacrylshikonin is a promising agent for developing an improved strategy for radiotherapy against tumors, it inhibits the proliferation of MCF-7 cells in vitro by inducing apoptosis through the downregulation of Bcl-2, upregulation of Bax and partial inactivation of the NF-κB pathway. Dimethylacrylshikonin inhibits agonist-induced relaxation at lower concentrations and induces vasocontraction at higher concentrations. |
| CFN96475 | Triptoquinone A Triptoquinone A may be a useful candidate for the development of a drug as a potent inhibitor of iNOS gene over-expression. Triptoquinone A has anti-inflammatory activity, it prevents ndotoxin-or interleukin-1 beta-promoted induction of nitric oxide synthase in vascular smooth muscle, thus inhibiting development of L-arginine-induced vasorelaxation. |
