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  • Stigmasterol


    Stigmasterol, a soy lipid-derived phytosterol, is an antagonist of the bile acid nuclear receptor FXR.[1] Stigmasterol, isolated from the bark of Butea monosperma, has thyroid inhibitory, anti-peroxidative and hypoglycemic effects .[2] Stigmasterol has potential anti-osteoarthritic properties, ...
  • Isoliquiritigenin


    Isoliquiritigenin(ILTG), a flavonoid constituent in the root of Glycyrrhiza glabra, has vasorelaxant effect, anti-platelet, anti-allergic and antiviral activities, also has protective effects in transient middle cerebral artery occlusion-induced focal cerebral ischemia in rats.[1] Insampaed...
  • Kazinol B


    Kazinol B, an isoprenylated flavan, inhibits the NO synthesis with an IC50 of 21.6 μM, has inhibition of nitric oxide production on LPS-activated macrophages.[1] Kazinol B improves insulin sensitivity via Akt and AMPK activation in 3T3-L1 adipocytes, it might be a therapeutic candidate f...
  • Annonacin


    Annonacin, a natural lipophilic mitochondrial complex I inhibitor, can increase phosphorylation of tau in the brain of FTDP-17 transgenic mice, and induce nigral and striatal neurodegeneration in rats: possible relevance for atypical parkinsonism in Guadeloupe.[1,2] Annonacin in Asimina triloba ...
  • Ergosterol peroxide


    Ergosterol peroxide(EPO)  is a major antitumor sterol produced by edible or medicinal mushrooms, the bacterial metabolites of EPO play a significant role in its cytotoxic activity against human colorectal cancer cells. [1] Ergosterol peroxide can exert antitumor activity in multiple myeloma...
  • Neochlorogenic acid


    Neochlorogenic acid (NCA) is a natural polyphenolic compound found in dried fruits and other plants, has shown that phenolic acids including NCA have outstanding antioxidant, antibacterial, antiviral, and antipyretic activities, it also exerts neuroprotective effects through the inhibition of pro...
  • (-)-Epigallocatechin(EGC)


    (-)-Epigallocatechin (EGC) can suppress oxidation of plasma low density lipoprotein (LDL) in vitro.[1] Epigallocatechin activates haem oxygenase-1 expression via protein kinase Cdelta and Nrf2.[2] Cu(2+) with (-)-epigallocatechin (EGC) facilitated DNA cleavage, while Ag+ with EGC showed a ...
  • Kaurenoic acid


    Kaurenoic acid, a diterpene isolated from Copaifera langsdorffii oleo-resin, has cytotoxic and embryotoxic effects.[1] Kaurenoic acid has anti-inflammatory potential in acetic acid-induced colitis, decreases in MDA level, an indicator of lipoperoxidation in colon tissue. [2] Kaurenoic acid...
  • Stigmasterol glucoside


    Stigmasterol glucoside, a constituent of Adenanthera pavonina seed and leaf, may be a plant anticancer agent.[1,2]
  • Berberine


    Berberine, a naturally occurring isoquinoline alkaloid, has been shown to possess anti-inflammatory and antitumor properties in some in vitro systems; berberine-induced apoptosis of human prostate cancer cells is mediated primarily through the caspase-dependent pathway, the effectiveness of ...
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