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  • Formononetin


    Formononetin causes vascular relaxation via endothelium/NO-dependent mechanism and endothelium-independent mechanism which involves the activation of BK(Ca) and K(ATP) channels.[1] Formononetin-treated Ovx rats has an increased bone osteoprotegerin-to-receptor activator for nuclear κB liga...
  • Ligustilide


    Ligustilide and senkyunolide A, two of the most abundant Ligusticum chuanxiong constituents, have vasorelaxation activities in contractions to various contractile agents in rat isolated aorta. [1] Ligustilide, one of the main compounds of Danggui essential oil, possesses antinociceptiv...
  • Beta-Sitosterol


    Beta-Sitosterol a main dietary phytosterol found in plants, may have the potential for prevention and therapy for human cancer, β-sitosterol induces apoptosis in HT116 cells is associated with a decreased expression of the anti-apototic Bcl-2 protein and mRNA and a concomitant increase of th...
  • Ginsenoside Compound K


    Ginsenoside compound K (C-K) is a metabolite of the protopanaxadiol-type saponins of Panax ginseng C.A. Meyer (Araliaceae), has long been used to treat against the development of cancer, inflammation, allergies, and diabetes; C-K acts as a unique HUVEC migration inhibitor by regulating MMP expres...
  • Rutin


    Rutin is a natural antioxidant, all doses can diminish reactive oxygen species and high doses (10-100 microM) decrease malondialdehyde concentration; induce favorable changes in the antioxidant defense system of cultured HepG2 that prevent or delay conditions which favor cellular oxidative s...
  • Hydroxysafflor yellow A


    Hydroxysafflor yellow A (HSYA), isolated from the dried flower of Carthamus tinctorius L. , which is extensively used in traditional Chinese medicine to treat cirrhosis, can protect against chronic carbon tetrachloride-induced liver fibrosis, might be a promising antifibrotic agent in chroni...
  • 6-Gingerol


    6-Gingerol, a natural product of ginger, has been known to possess anti-tumorigenic and pro-apoptotic activities, it stimulates apoptosis through upregulation of NAG-1 and G1 cell cycle arrest through downregulation of cyclin D1, multiple mechanisms appear to be involved in 6-gingerol action, inc...
  • Asperosaponin VI


    Asperosaponin VI (ASA VI) is a kind of saponin in the medicinal herb Dipsacus asper Wall which has long been used as an antiosteoporosis drug, exhibits a significant induction of proliferation, differentiation and mineralization in MC3T3-E1 and primary osteoblastic cells, it may induce osteoblast...
  • Cyanidin-3-O-glucoside chloride


    Cyanidin-3- O -glucoside, is one of the main component of mulberry anthocyanins,has protective effects from blackberry extract against peroxynitrite-induced endothelial dysfunction and vascular failure.[1] Cyanidin-3- O -glucoside exhibits strong antioxidant activities including DPPH radica...
  • Pachymic acid


    Pachymic acid (PA) is a natural triterpenoid known to inhibit the phospholipase A2 (PLA(2)) family of arachidonic acid (AA)-producing enzymes, PA-treatment decreases bad phosphorylation, increases Bcl-2 phosphorylation, and activates caspases-9 and -3, it also decreases the expression and ac...
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