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  • Geniposide


    Geniposide, a major iridoid found in fruit, is widely used in Asian countries for its anti-inflammatory, and anti-apoptotic activities, the anti-apoptotic activities is due to its modulation of and -related factors (p53, Bax, Bcl-2 and Caspase-3) in LPS-induced mouse mastitis. [1] Geniposid...
  • Hesperetin 7-O-glucoside


    Hesperetin 7-O-glucoside and prunin are direct precursors of naringin and neohesperidin, respectively, in C. aurantium , because of the capacity of glucosyltransferase from cell-free extracts of C. aurantium tissues to glucosylate naringenin and hesperetin .[1]
  • Palmatine


    Palmatine , a protoberberine alkaloid, is present in preparations from medicinal plants such as Coptis chinensis and Corydalis yanhusuo, palmatine activates the AhR-CYP1A pathway in HepG2 monolayer, while the potential for CYP1A induction is irrelevant in cell systems which are closer to the...
  • Lithospermic acid


    Lithospermic acid (LSA) was originally isolated from the roots of Salvia mitiorrhiza , has antioxidant effects,   is a competitive inhibitor of xanthine oxidase (XO), can directly scavenge superoxide and inhibit superoxide production in vitro, and presents hypouricemic and anti-inflamm...
  • Luteolin-7-O-glucoside


    Luteolin-7-O-glucoside and luteolin at concentrations lower than 20 muM, significantly suppresses the productions of nitric oxide and prostaglandin E-2 (PGE(2)) in bacterial lipopolysaccharide activated-mouse macrophage RAW264.7 cells without introducing cytotoxicity; the inhibitory eff...
  • Amygdalin


    Amygdalin induces apoptotic cell death in human DU145 and LNCaP prostate cancer cells by caspase-3 activation through down-regulation of Bcl-2 and up-regulation of Bax,suggests it may offer a valuable option for the treatment of prostate cancers.[1] Amygdalin suppresses the prostaglandin E(2) sy...
  • Medicarpin


    Medicarpin, a legume phytoalexin, acts as an estrogen receptor (ER) agonist, can stimulate osteoblast differentiation likely via ERβ, promote achievement of peak bone mass, and is devoid of uterine estrogenicity; in addition, given its excellent oral bioavailability, it can be potential...
  • Alpinetin


    Alpinetin is a type of novel plant flavonoid derived from Alpinia katsumadai Hayata, possesses strong anti-hepatoma effects, can suppress HepG2 cell proliferation and arrested cells in the G0/G1 phase by up-regulating the expression levels of p-MKK7, and   the antitumor effect of A...
  • Ophiopogonin B


    Ophiopogonin B (OP-B) is a bioactive component of Radix Ophiopogon Japonicus, which is often used in Chinese traditional medicine to treat pulmonary disease, it is a prospective inhibitor of PI3K/Akt and may be used as an alternative compound to treat NSCLC, it also induces apoptosis, mitotic cat...
  • Benzoylaconine


    Benzoylaconine and aconitine can induce reproductive toxicity in BeWo Cell, the amino acid metabolism was the main metabolic pathway and responsible for the placental and fetal toxicity of them.[1]
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