Bioactive Products
| A unique collection of 552 Anti-inflammatory natural compound library for Anti-inflammatory screening and New Anti-inflammatory drug research | ||
| Catalog No: | B72a26 | Anti-inflammatory Compound Library Screening Details |
| Size: | 1mg/well * 552 Compounds 2mg/well * 552 Compounds | |
| Cat. No. | Information |
| CFN97192 | Voleneol 1β,6α-Dihydroxyeudesm-4(15)-ene (Voleneol,DE) can attenuate the lipopolysaccharide (LPS)-induced inflammation in BV2 microglial cells, it also can dose-dependently suppress the protein expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2),suggest thats DE may be a good candidate to regulate LPS-induced inflammatory response. |
| CFN97198 | Canniprene Canniprene has anti-inflammatory activity, it can potently inhibit the production of inflammatory eicosanoids via the 5-lipoxygenase pathway (IC50=0.4uM) and also can affect the generation of prostaglandins via the cyclooxygenase/microsomal prostaglandin E2 synthase pathway (IC50 =10 uM). |
| CFN97205 | Laurifoline Laurifoline is a potential NF-κB inhibitor and a potential β2 -adrenegic receptor agonist, it can not only inhibit Pseudomonas aeruginosa PAK strain-induced inflammatory responses via a negative regulation of the Braf protein that participates in MAPK signaling pathway but also activate the β2 -adrenegic receptor. Laurifoline may show anti-HBV activities in vitro using the HBV transfected Hep G2.2.15 cell line. |
| CFN97220 | Acanthoside B Acanthoside has inhibitory effects on the allergic inflammation. |
| CFN97233 | Obacunone Obacunone is a novel activator of Nrf2, which exhibits anti-cancer, anti-inflammatory, antivirulence, insecticidal, anti-proliferative and anti-aromatase activities. Obacunone stimulates muscle hypertrophy and prevents obesity and hyperglycemia, and that these beneficial effects are likely to be mediated through the activation of TGR5 and inhibition of PPARγ transcriptional activity. Obacunone significantly inhibits aromatase activity in an in vitro enzyme assay with an IC50 value of 28.04 μM, and it also inhibits the p38 MAPK signaling pathway. |
