Bioactive Products
| A unique collection of 674 anticancer natural compounds for high throughput screening (HTS) and New anticancer drug research | ||
| Catalog No: | B91 | Anticancer Compound Library Screening Details |
| Size: | 1mg/well * 674 Compounds 2mg/well * 674 Compounds | |
| Cat. No. | Information |
| CFN00139 | Tenuazonic acid Tenuazonic acid, an active component in the A. alternata toxin.Tenuazonic acid exhibits a strong inhibition in photosystem II (PSII) activity, it causes cell necrosis of host-plants by oxidative damage from chloroplast-mediated ROS eruption, and enhances the plant's resistances against rose aphids. |
| CFN00142 | Tirandamycin B Tirandamycin B is a BmAsnRS inhibitor, it is a leading anti-filarial drug . Tirandamycin B has antitumor and antibacterial activities. |
| CFN98917 | Pinobanksin Pinobanksin and some of its ester derivatives from Sonoran propolis have apoptotic induction in a B-cell lymphoma cell line. Pinobanksin possesses considerable antimutagenic properties against ofloxacin-induced bleaching of E. gracilis. Pinobanksin inhibits peroxidation of low density lipoprotein and it has electron donor properties reducing alpha-tocopherol radicals. |
| CFN98918 | Galangin Galangin is an agonist/antagonist of the arylhydrocarbon receptor, and also shows inhibition of CYP1A1 activity. Galangin has anti-proliferation, anti-metastatic, anti-inflammatory, vasorelaxant, antiviral, anti-allergic inflammatory,anti-obesity effects; it may be a potential candidate for the treatment of vitiligo. Galangin can inhibit Topo I activity and reduce the unwinding rate of single stranded DNNA in tumor cells, which plays an important role in induction of A549 and H46 cell apoptosis. Galangin shows an inhibitory effect on acetylcholinesterase (AChE) activity with the IC(50) of 120 microM; it also inhibits ERK, NF-κB-p65 and proinflammatory gene expression. |
| CFN98923 | Andrographolide Andrographolide is an antiinflammatory, antiviral, anti-cancer , hepatoprotective, antithrombotic, hypotensive and antiatherosclerotic drug, it can cure hyperpigmentation disorders. Andrographolide protects against chemical-induced oxidative damage by up-regulating the gene transcription and activity of antioxidant enzymes in various tissues.Andrographolide has potential as a leading compound in the prevention or treatment of obesity and insulin resistance, can ameliorate lipid metabolism and improve glucose use in mice with HFD-induced obesity. |
