Bioactive Products
A unique collection of 674 anticancer natural compounds for high throughput screening (HTS) and New anticancer drug research | ||
Catalog No: | B91 | Anticancer Compound Library Screening Details |
Size: | 1mg/well * 674 Compounds 2mg/well * 674 Compounds |
Cat. No. | Information |
CFN98872 | Magnolol Magnolol is a dual agonist of both RXRα and PPARγ, with EC50 values of 10.4 μM and 17.7 μM, respectively. Magnolol has antifungal, antibacterial, anti-oxidative, antidepressant-like, anti- tumor, and neuroprotective effects, it also prevents skin photoaging in UVB-irradiated hairless mice. Magnolol has a wide spectrum of targets including TNF-α, NF-KB, GSK3β. |
CFN98877 | Myricetin Myricetin, a natural flavonoid with anti-amyloidogenic, anti-oxidant, anticancer, antidiabetic and anti-inflammatory properties, is a novel inhibitor of MEK1 activity and inhibits glucose uptake in isolated rat adipocytes . It also inhibits PI3Kγ with Kd of 0.17 μM. Myricetin exerts potent anti-photoaging activity by regulating MMP-9 expression through the suppression of Raf kinase activity. Myricetin can enhance osteogenic differentiation of hBMSCs by activating the Wnt/β-catenin signaling. |
CFN98885 | 9,13-Epidioxy-8(14)-abieten-18-oic acid 9,13β-Epidioxy-8(14)-abieten-18-oic acid has anti-inflammatory activities, it exhibits moderate activities on NO levels in LPS-stimulated murine microglia BV2 cells, with IC50 values of 57.3 ± 0.2 uM. It is also a potential antitumor-promoting diterpenoid, it shows potent inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by the tumor promoter 12-O-tetradecanoylphorbol 13-acetate. 9 α ,13 β -Epidioxyabeit-8(14)en-18-oic acid may contribute to the growth inhibitory effect of the pine needles and may play an important role in the allelopathy of red pine. |
CFN00101 | Aburatubolactam A Aburatubolactam A is an inhibitor of superoxide anion generation. It has demonstrated cytotoxic activity against P388 murine leukemia cell lines (IC50 = 26 ug/mL) and inhibits TPA-induced superoxide anion generation by human neutrophils; enhanced levels of superoxide anion is thought to be closely related to inflammation, cancer, and aging. |
CFN00102 | Aflastatin A Aflastatin A exhibits antimicrobial activity against some bacteria, yeasts and fungi, it is a specific inhibitor of aflatoxin production by Aspergillus parasiticus, inhibits a very early step in aflatoxin biosynthesis prior to the transcription of aflR and can influence glucose metabolism in the fungus. Aflastatin A has antitumor activity. Aflastatin A inhibits an early step in melanin production, which suppresses the expression of PKS1. |