Bioactive Products
| A unique collection of 674 anticancer natural compounds for high throughput screening (HTS) and New anticancer drug research | ||
| Catalog No: | B91 | Anticancer Compound Library Screening Details |
| Size: | 1mg/well * 674 Compounds 2mg/well * 674 Compounds | |
| Cat. No. | Information |
| CFN99129 | Cucurbitacin B Cucurbitacin B, an effective HIF-1 inhibitor, has antitumor activity, it inhibits proliferation and induces apoptosis via STAT3 pathway inhibition in A549 lung cancer cells. It inhibited AKT signaling activation through up-regulation of PTEN. |
| CFN99130 | Theaflavin 3,3'-di-O-gallate Theaflavin-3,3'-digallate(TF3), an inducer of oxidative stress, which has anti-inflammatory and cancer chemopreventive actions, it reduces tumor angiogenesis by downregulating HIF-1αand VEGF; suggests that TF3 might serve as a potential anti-angiogenic agent for cancer treatment. TF3 and lactic acid combinations can reduce Herpes Simplex Virus(HSV) infectivity. |
| CFN99132 | 10-Gingerol 10-Gingerol has anti-cancer, anti-neuroinflammatory, and anti-bacterial effects, it effectively inhibits the growth of the oral pathogens, and inhibits exogenous ghrelin deacylation.10-Gingerol induces [Ca2+]i rise by causing Ca2+ release from the endoplasmic reticulum and Ca2+ influx from non-L-type Ca2+ channels in SW480 cancer cells.10-Gingerol-induced apoptosis was accompanied by phosphorylation of the mitogen-activated protein kinase (MAPKs) family, c-Jun N-terminal kinase (JNK), p38 MAPK (p38), and extracellular signal-regulated kinase (ERK). |
| CFN99133 | Dendrobine Dendrobine is an antagonist of β-alanine, taurine and of presynaptic inhibition in the frog spinal cord. Dendrobine has antiviral, and antitumor activities; it can inhibit the growth of A549 cells through inducing apoptosis, which is partially dependent on mitochondrial-mediated pathway; dendrobine treatment decreased mitochondrial membrane potential (MMP), improved the expression of Bax and inhibited the expression of Bcl-2. |
| CFN99136 | Ononin Ononin is an additional growth inhibitor in soils associated with the weed, Pluchea lanceolata, it can significantly inhibit root and shoot growth of mustard at 1×10(-4) M, 5×10(-4) M, and 1×10(-3)M , and inhibit the growth of pathogen such as Enterococcus sp., Enterobacter sp. and can promote the growth of probiotics such as Bifidobacteria sp. and Lactobacilli sp. Ononin has weak DPPH·free radical and the superoxide anion free radical scavenging capacity. |
