Bioactive Products
| A unique collection of 674 anticancer natural compounds for high throughput screening (HTS) and New anticancer drug research | ||
| Catalog No: | B91 | Anticancer Compound Library Screening Details |
| Size: | 1mg/well * 674 Compounds 2mg/well * 674 Compounds | |
| Cat. No. | Information |
| CFN99067 | 3alpha-Akebonoic acid 3α-Akebonoic acid shows interesting in vitro growth inhibitory activity against human tumor A549 and HeLa cell lines, it also shows significant in vitro α-glucosidase inhibitory activity. 3α-Akebonoic acid can interfer with presenilin-1 (PS1)/ β-site APP-cleaving enzyme 1 (BACE1) interaction and reduces Aβ production, the chemical interference of PS1/BACE1 interaction is a promising strategy for Alzheimer’s disease therapeutics. |
| CFN99077 | Ganodermanontriol Ganodermanontriol has anti-cancer, hepatoprotective, anti-inflammatory, and antioxidative activities, it also shows a strong anticomplement activity against the classical pathway (CP) of the complement system with IC(50) values of 17.2 microM. Ganodermanontriol is active as an anti-HIV-1 agent with an inhibitory concentration of 7.8 micrograms ml-1.It has a wide spectrum of targets including HO-1, PI3K/Akt and p38 kinases. |
| CFN99083 | Coccinic acid Coccinic acid shows inhibitory effects against colorectal carcinoma HCT-15 and oral epithelial cell line KB-3-1.Mixture of coccinic acid and anwuweizonic acid shows significant inhibitory activity against human decidual cells and rat luteal cells in vitro, suggests that it has antifertility activity. |
| CFN99208 | Squalene Squalene, a naturally occurring substance found in plants, animals and humans, is a component of some adjuvants that is added to vaccines to enhance the immune response.Squalene shows several pharmacological properties such as hypolipidemic, hepatoprotective, cardioprotective, antioxidant, and antitoxicant activity. Squalene can significantly suppress colonic aberrant crypt foci (ACF) formation and crypt multiplicity strengthens the hypothesis that squalene possesses chemopreventive activity against colon carcinogenesis. |
| CFN99215 | Adenanthin Adenanthin is a novel NF-κB and nucleophilic cysteines inhibitor, it has bacteriostatic, antiinflammatory, and antitumour activities. Adenanthin also has antileukemic activity through targeting peroxiredoxin I/II. Adenanthin can serve as the development of Prx I– and Prx II–targeted therapeutic agents. |
