Bioactive Products
| A unique collection of 223 Neuroprotection natural compounds for high throughput screening (HTS) | ||
| Catalog No: | B72a21 | Neuroprotection Compound Library Screening Details |
| Size: | 1mg/well * 223 Compounds 2mg/well * 223 Compounds | |
| Cat. No. | Information |
| CFN90035 | beta-Estradiol Estradiol, or more precisely, 17β-estradiol, is a human sex hormone and steroid, and the primary female sex hormone. Beta-estradiol has been considered to be a neurotrophic agent, beta-estradiol at a dose of 0.25 microg/day prevents ischemia-induced learning disability and neuronal loss at early stages after transient forebrain ischemia, possibly via a receptor-mediated pathway without attenuating free radical neurotoxicity. |
| CFN98726 | Nobiletin Nobiletin, a citrus flavonoid isolated from citrus peels like in tangerine, which has anti-inflammatory and anti-tumor activities, it could be a potential protective agent for the prevention and treatment of restenosis after angioplasty. Nobiletin downregulated the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase 2 (COX-2), suppressed cell viability through AKT pathways. |
| CFN90043 | Dehydroepiandrosterone Dehydroepiandrosterone is an important endogenous steroid hormone, which is an androgen receptor antagonist and an estrogen receptor agonist. Dehydroepiandrosterone can treat symptoms, and signs of vulvovaginal atrophy along with libido in postmenopausal women. Dehydroepiandrosterone is a neuroactive hormone, it in co-operation with other hormones and transmitters significantly affects some aspects of human mood, and modifies some features of human emotions and behavior; it has been reported that its administration can increase feelings of well-being and is useful in ameliorating atypical depressive disorders, it has neuroprotective and antiglucocorticoid activity and modifies immune reactions. |
| CFN90046 | D-Mannitol D-Mannitol, a specific hydroxyl free radical scavenger, can reduce the developmental toxicity of hydroxyurea in rabbits; it has thermal properties and could be as a Phase Change Material (PCM) for latent heat storage system; it is a potential diagnostic marker for aspergillosis. D-mannitol has neuroprotectant effect in reducing the sensory neurological disturbances seen in ciguatera poisoning, it does not act purely as an osmotic agent to reduce swelling of nerves, but involves a more complex action dependent on the Na(v) channel subtype, possibly to alter or reduce toxin association. |
| CFN90047 | Norepinephrine Norepinephrine is a peripheral vasoconstrictor by acting on alpha-adrenergic receptors, it can up-regulate the expression of vascular endothelial growth factor, matrix metalloproteinase (MMP)-2, and MMP-9 in nasopharyngeal carcinoma tumor cells. Norepinephrine can stimulates apoptosis in adult rat ventricular myocytes by activation of the β-adrenergic pathway. Noradrenergic system may play a significant role in modulating the development of ischemic neuronal damage. |
