11alpha,12alpha-Oxidotaraxerol palmitate | CAS:495389-95-2

11alpha,12alpha-Oxidotaraxerol palmitate

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Description:

11alpha,12alpha-Oxidotaraxerol palmitate shows selective cytotoxicity against HCT-8, Bel-7402, BGC-823, A549 and A2780.

In vitro:

Journal of Chinese Institute of Food Science & Technology,2014,14(3):196-204.

Isolation, purification, elucidation and cytotoxicity activity on oxidotaraxerone and oxidationtaraxerol of Cirsium setosum (Willd.) MB[Reference: WebLink]

To investigate chemical constituents contained in cytotoxic petroleum ether-soluble portion from the ethanol extracts of Cirsium setosum (Willd.) MB, and evaluate their cytotoxic activity in vitro.
METHODS AND RESULTS:
The constituents were separated and purified by various chromatographic methods including silica gel and Sephadex LH-20, and their structures were elucidated by spectroscopic methods including NMR, MS methods and comparison with literature. Three oxidotaraxerane triterpenoids were isolated from the petroleum ether fraction of ethanolic extract of Cirsium setosum, and determined as 11α, 12α-oxidotaraxerone, 11α, 12α-oxidotaraxerol and 11alpha,12alpha-Oxidotaraxerol palmitate.
CONCLUSIONS:
To the best of our knowledge, this is the first report showing the presence of all the compounds in the genus Cirsium. In the in vitro assays, three compounds showed selective cytotoxicity against HCT-8, Bel-7402, BGC-823, A549 and A2780.

11alpha,12alpha-Oxidotaraxerol palmitate Description

Source:	The herbs of Cirsium setosum (Willd.) MB.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	11alpha,12alpha-Oxidotaraxerol palmitate
Price:
CAS No.:	495389-95-2
Catalog No.:	CFN96827
Molecular Formula:	C₄₆H₇₈O₃
Molecular Weight:	679.11 g/mol
Purity:	>=98%
Type of Compound:	Triterpenoids
Physical Desc.:	Powder
Source:	The herbs of Cirsium setosum (Willd.) MB.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Cytotoxic Compound Library Triterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.4725 mL	7.3626 mL	14.7252 mL	29.4503 mL	36.8129 mL
5 mM	0.2945 mL	1.4725 mL	2.945 mL	5.8901 mL	7.3626 mL
10 mM	0.1473 mL	0.7363 mL	1.4725 mL	2.945 mL	3.6813 mL
50 mM	0.0295 mL	0.1473 mL	0.2945 mL	0.589 mL	0.7363 mL
100 mM	0.0147 mL	0.0736 mL	0.1473 mL	0.2945 mL	0.3681 mL

CFN89221	Germanicol	465-02-1	426.72	C₃₀H₅₀O
CFN96961	Germanicol acetate	10483-91-7	468.76	C₃₂H₅₂O₂
CFN99679	beta-Amyrin acetate	1616-93-9	468.8	C₃₂H₅₂O₂
CFN97009	beta-Amyrin palmitate	5973-06-8	665.1	C₄₆H₈₀O₂
CFN97099	beta-Amyrone	638-97-1	424.7	C₃₀H₄₈O
CFN97528	9(11),12-Oleanadien-3-ol	94530-87-7	424.7	C₃₀H₄₈O
CFN94009	12-Oleanene-3,6-diol	41498-79-7	442.72	C₃₀H₅₀O₂
CFN94010	Daturaolone	41498-80-0	440.71	C₃₀H₄₈O₂
CFN96835	Rubiprasin B	125263-66-3	500.76	C₃₂H₅₂O₄
CFN96836	Rubiprasin A	125263-65-2	516.76	C₃₂H₅₂O₅