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12-Epinapelline
12-Epinapelline
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 12-Epinapelline
Price: $238 / 20mg
CAS No.: 110064-71-6
Catalog No.: CFN90663
Molecular Formula: C22H33NO3
Molecular Weight: 359.5 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The roots of Aconitum kusnezoffii Reichb.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: 12-Epinapelline is a natural product from Aconitum kusnezoffii Reichb.
12-Epinapelline Description
Source: The roots of Aconitum kusnezoffii Reichb.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.7816 mL 13.9082 mL 27.8164 mL 55.6328 mL 69.541 mL
5 mM 0.5563 mL 2.7816 mL 5.5633 mL 11.1266 mL 13.9082 mL
10 mM 0.2782 mL 1.3908 mL 2.7816 mL 5.5633 mL 6.9541 mL
50 mM 0.0556 mL 0.2782 mL 0.5563 mL 1.1127 mL 1.3908 mL
100 mM 0.0278 mL 0.1391 mL 0.2782 mL 0.5563 mL 0.6954 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chemistry of Natural Compounds, 2005,41(5):609.
Crystal and Molecular Structure of 12-Epinapelline[Reference: WebLink]

METHODS AND RESULTS:
The article examines the crystal and molecular structure of 12-Epinapelline. Previous investigations showed that the conformation of ring A in crystal structures of napelline-type alkaloids depended on the presence or absence of an intramolecular H-bond between an alpha-oriented C1 hydroxyl and the N atom.
CONCLUSIONS:
Thus, ring A in 12-epilucidusculin had the boat conformation and in acophine it adopted the twist or chair conformation.
CFN99502Acoforestinine110011-77-3645.79C35H51NO10
CFN893298-Deacetylyunaconitine93460-55-0617.73C33H47NO10
CFN99503Yunaconitine70578-24-4659.77C35H49NO11
CFN893623-Acetylyunaconitine80787-51-5701.80C37H51NO12
CFN99720Bulleyaconitine A107668-79-1643.8C35H49NO10
CFN89455Carmichaenine D2065228-62-6513.62C29H39NO7
CFN89454Carmichaenine C2065228-61-5527.64C30H41NO7
CFN93029Foresaconitine73870-35-6627.77C35H49NO9
CFN906603-Deoxyaconitine3175-95-9629.74C34H47NO10
CFN99915Aconitine302-27-2645.75C34H47NO11
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