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17-Methylparsonsianidine
17-Methylparsonsianidine
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Product Name 17-Methylparsonsianidine
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CAS No.: 135637-68-2
Catalog No.: CFN00381
Molecular Formula: C23H35NO9
Molecular Weight: 469.53 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The leaves of Parsonsia laevigata
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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Related Screening Libraries
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Biological Activity
Description: Reference standards.
In vitro:
Journal of Chemical Ecology, 1997,23(7):1703-1713.
Pyrrolizidine Alkaloids Mediate Host-Plant Recognition by Ovipositing Females of an Old World Danaid Butterfly, Idea leuconoe[Reference: WebLink]

METHODS AND RESULTS:
A giant danaid butterfly, Idea leuconoe, specializes on apocynaceous plants such as Parsonsia laevigata, which has been reported to contain pyrrolizidine alkaloids. Females of I. leuconoe deposited eggs in response to methanolic extract of P. laevigata, and subsequent bioassay-guided fractionation of the extract revealed that phytochemicals crucial for host recognition by ovipositing females are Parsonsia-specific macrocyclic pyrrolizidine alkaloids including parsonsianine, parsonsianidine, and 17-Methylparsonsianidine. Parsonine, another P. laevigata pyrrolizidine component with a keto-dihydropyrrolizine moiety that is closely related in structure to male pheromones of the butterfly, and several nonhost pyrrolizidine alkaloids were entirely inactive.
CONCLUSIONS:
We interpret these data as strong evidence for an ancestral association through herbivory between danaid butterflies and pyrrolizidine alkaloids.
17-Methylparsonsianidine Description
Source: The leaves of Parsonsia laevigata
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
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IF=36.216(2019)

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Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1298 mL 10.6489 mL 21.2979 mL 42.5958 mL 53.2447 mL
5 mM 0.426 mL 2.1298 mL 4.2596 mL 8.5192 mL 10.6489 mL
10 mM 0.213 mL 1.0649 mL 2.1298 mL 4.2596 mL 5.3245 mL
50 mM 0.0426 mL 0.213 mL 0.426 mL 0.8519 mL 1.0649 mL
100 mM 0.0213 mL 0.1065 mL 0.213 mL 0.426 mL 0.5324 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Phytochemistry,1991,30(5): 1737–1739.
Macrocyclic pyrrolizidine alkaloids from Parsonsia laevigata[Reference: WebLink]

METHODS AND RESULTS:
Parsonsianidine, a new minor macrocyclic pyrrolizidine alkaloid having two ethyl side-chains at C-11 and C-20, was isolated along with parsonsianine from the leaves of Parsonsia laevigata. Its structure was determined by spectral analyses. 17-Methylparsonsianidine, having the same plane structure as spiranine, was also identified.
CFN00347Axillarine19637-66-2369.41C18H27NO7
CFN00348Axillaridine23506-96-9353.41C18H27NO6
CFN00349Othonnine119565-25-2353.41C18H27NO6
CFN00356Croalbidine41714-30-1371.43C18H29NO7
CFN00371Grantaline83482-61-5351.40C18H25NO6
CFN0038117-Methylparsonsianidine135637-68-2469.53C23H35NO9
CFN00383Spiracine77156-24-2485.53C23H35NO10
CFN00397Parsonsianidine135601-81-9455.50C22H33NO9
CFN00398Parsonsianine131683-36-8441.48C21H31NO9
CFN00433Trichodesmine548-90-3353.41C18H27NO6
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