19-Oxocinobufotalin | CAS:24512-60-5 | Manufacturer ChemFaces

19-Oxocinobufotalin

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Description:

19-Oxocinobufotalin 3-adipoylarginine ester shows significant inhibition effect against human hepatocellular carcinoma cell line SMMC-7721 in vitro.

In vitro:

J Asian Nat Prod Res. 2011 Feb;13(2):111-6.

Cytotoxic constituents from the skin of the toad Bufo bufo gargarizans.[Pubmed: 21279874 ]

METHODS AND RESULTS:
To study the chemical composition of the skin of Bufo bufo gargarizans, various chromatographic methods were used in the isolation procedures and the structures of isolated compounds were determined based on NMR and MS analysis. As a result, two new compounds were isolated from its ethanolic extract and characterized as N-[2-hydroxy-2-(4-hydroxyphenyl)ethyl]-N-methylurea (1) and 19-Oxocinobufotalin 3-adipoylarginine ester (2), together with 11 known compounds.
CONCLUSIONS:
Isolated bufadienolides showed significant inhibition effect against human hepatocellular carcinoma cell line SMMC-7721 in vitro.

19-Oxocinobufotalin Description

Source:	The glandular body of Bufo bufo gargarizans Cantor.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	19-Oxocinobufotalin
Price:	$413 / 5mg
CAS No.:	24512-60-5
Catalog No.:	CFN91016
Molecular Formula:	C₂₆H₃₂O₈
Molecular Weight:	472.53 g/mol
Purity:	>=98%
Type of Compound:	Steroids
Physical Desc.:	Powder
Source:	The glandular body of Bufo bufo gargarizans Cantor.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Steroids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.1163 mL	10.5813 mL	21.1627 mL	42.3254 mL	52.9067 mL
5 mM	0.4233 mL	2.1163 mL	4.2325 mL	8.4651 mL	10.5813 mL
10 mM	0.2116 mL	1.0581 mL	2.1163 mL	4.2325 mL	5.2907 mL
50 mM	0.0423 mL	0.2116 mL	0.4233 mL	0.8465 mL	1.0581 mL
100 mM	0.0212 mL	0.1058 mL	0.2116 mL	0.4233 mL	0.5291 mL

CFN90151	Bufarenogin	17008-65-0	416.51	C₂₄H₃₂O₆
CFN91017	Pseudobufarenogin	17008-69-4	416.51	C₂₄H₃₂O₆
CFN98545	Bufotaline	471-95-4	444.56	C₂₆H₃₆O₆
CFN98543	Resibufogenin	465-39-4	384.51	C₂₄H₃₂O₄
CFN91013	Resibufagin	20987-24-0	398.49	C₂₄H₃₀O₅
CFN90579	Deacetylcinobufagin	4026-95-3	400.52	C₂₄H₃₂O₅
CFN98544	Cinobufagin	470-37-1	442.55	C₂₆H₃₄O₆
CFN91012	19-Oxocinobufagin	24512-59-2	456.53	C₂₆H₃₂O₇
CFN93070	Marinobufagenin	470-42-8	400.51	C₂₄H₃₂O₅
CFN93073	Desacetylcinobufotalin	4099-30-3	416.51	C₂₄H₃₂O₆